SLC2A3 (solute carrier family 2 member 3)

2003-05-01  

Identity

HGNC
SLC2A3
LOCATION
12p13.31
LOCUSID
6515
ALIAS
GLUT3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6515
MIM: 138170
HGNC: 11007
Ensembl: ENSG00000059804

Variants:

dbSNP: 6515
ClinVar: 6515
TCGA: ENSG00000059804
COSMIC: SLC2A3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000059804ENST00000075120P11169
ENSG00000059804ENST00000544291F5GYR5
ENSG00000059804ENST00000544936F5GYX0

Expression (GTEx)

0
100
200
300
400
500
600
700
800
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Hexose transportREACTOMER-HSA-189200
Glucose transportREACTOMER-HSA-70153
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Facilitative Na+-independent glucose transportersREACTOMER-HSA-428790
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Metabolism of water-soluble vitamins and cofactorsREACTOMER-HSA-196849
Vitamin C (ascorbate) metabolismREACTOMER-HSA-196836
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383967572024Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance.1
386259782024SLC2A3 promotes tumor progression through lactic acid-promoted TGF-β signaling pathway in oral squamous cell carcinoma.0
383967572024Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance.1
386259782024SLC2A3 promotes tumor progression through lactic acid-promoted TGF-β signaling pathway in oral squamous cell carcinoma.0
372585722023The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression.2
377218532023GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing.5
377506392023Concurrent presence of diabetes affects the GLUT3 programming of glucose metabolism in glioblastoma.0
372585722023The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression.2
377218532023GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing.5
377506392023Concurrent presence of diabetes affects the GLUT3 programming of glucose metabolism in glioblastoma.0
347812822022Peritoneal Expression of SGLT-2, GLUT1, and GLUT3 in Peritoneal Dialysis Patients.9
352601832022miR-3189-targeted GLUT3 repression by HDAC2 knockdown inhibits glioblastoma tumorigenesis through regulating glucose metabolism and proliferation.13
353166572022The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming.48
354664762022SLC2A3 variants in familial and sporadic congenital heart diseases in a Chinese Yunnan population.3
354844352022Evolutionary balance between foldability and functionality of a glucose transporter.7

Citation

Dessen P

SLC2A3 (solute carrier family 2 member 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42319/slc2a3-(solute-carrier-family-2-member-3)