Identity
HGNC
LOCATION
10q24.33
LOCUSID
ALIAS
LOSK,STK2,bA16H23.1,se20-9
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9748
MIM: 616563
HGNC: 11088
Ensembl: ENSG00000065613
Variants:
dbSNP: 9748
ClinVar: 9748
TCGA: ENSG00000065613
COSMIC: SLK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000065613 | ENST00000335753 | Q9H2G2 |
| ENSG00000065613 | ENST00000369755 | Q9H2G2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Oocyte meiosis | KEGG | ko04114 |
| Oocyte meiosis | KEGG | hsa04114 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31913659 | 2020 | Ste20-like Kinase-mediated Control of Actin Polymerization Is a New Mechanism for Thin Filament-associated Regulation of Airway Smooth Muscle Contraction. | 13 |
| 31913659 | 2020 | Ste20-like Kinase-mediated Control of Actin Polymerization Is a New Mechanism for Thin Filament-associated Regulation of Airway Smooth Muscle Contraction. | 13 |
| 29534578 | 2018 | Ste20-like kinase is upregulated in glioma and induces glioma invasion. | 2 |
| 29534578 | 2018 | Ste20-like kinase is upregulated in glioma and induces glioma invasion. | 2 |
| 26094769 | 2015 | Identification of Tpr and α-actinin-4 as two novel SLK-interacting proteins. | 3 |
| 26094769 | 2015 | Identification of Tpr and α-actinin-4 as two novel SLK-interacting proteins. | 3 |
| 24958772 | 2014 | SLK-dependent activation of ERMs controls LGN-NuMA localization and spindle orientation. | 44 |
| 24958772 | 2014 | SLK-dependent activation of ERMs controls LGN-NuMA localization and spindle orientation. | 44 |
| 23985322 | 2013 | Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome. | 11 |
| 23985322 | 2013 | Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome. | 11 |
| 23209304 | 2012 | Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells. | 48 |
| 23209304 | 2012 | Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells. | 48 |
| 19525980 | 2009 | The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility. | 22 |
| 19525980 | 2009 | The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility. | 22 |
| 18287541 | 2008 | Ste20-related protein kinase LOSK (SLK) controls microtubule radial array in interphase. | 13 |
Citation
Dessen P
SLK (STE20 like kinase)
Atlas Genet Cytogenet Oncol Haematol. 2004-04-01
Online version: http://atlasgeneticsoncology.org/gene/42329/slk-(ste20-like-kinase)
