SPARCL1 (SPARC like 1)

2003-05-01  

Identity

HGNC
SPARCL1
LOCATION
4q22.1
LOCUSID
8404
ALIAS
MAST
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8404
MIM: 606041
HGNC: 11220
Ensembl: ENSG00000152583

Variants:

dbSNP: 8404
ClinVar: 8404
TCGA: ENSG00000152583
COSMIC: SPARCL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152583ENST00000282470Q14515
ENSG00000152583ENST00000282470A0A024RDE1
ENSG00000152583ENST00000418378Q14515
ENSG00000152583ENST00000418378A0A024RDE1
ENSG00000152583ENST00000434434C9JJR8
ENSG00000152583ENST00000458304E7EU82
ENSG00000152583ENST00000503414Q14515
ENSG00000152583ENST00000509407E9PC64
ENSG00000152583ENST00000512317D6RA29
ENSG00000152583ENST00000535835F5H331
ENSG00000152583ENST00000541496F5H1Y9
ENSG00000152583ENST00000543631F5H4Y3

Expression (GTEx)

0
500
1000
1500
2000
2500
3000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
387624892024Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation.0
387624892024Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation.0
368306032023The Matricellular Protein Hevin Is Involved in Alcohol Use Disorder.1
371805782023Identifying liver metastasis-related hub genes in breast cancer and characterizing SPARCL1 as a potential prognostic biomarker.1
368306032023The Matricellular Protein Hevin Is Involved in Alcohol Use Disorder.1
371805782023Identifying liver metastasis-related hub genes in breast cancer and characterizing SPARCL1 as a potential prognostic biomarker.1
351118442022SPARCL1 Is a Novel Prognostic Biomarker and Correlates with Tumor Microenvironment in Colorectal Cancer.6
351362092022The KDM6A-SPARCL1 axis blocks metastasis and regulates the tumour microenvironment of gastrointestinal stromal tumours by inhibiting the nuclear translocation of p65.4
355498062022Circular_0086414 induces SPARC like 1 (SPARCL1) production to inhibit esophageal cancer cell proliferation, invasion and glycolysis and induce cell apoptosis by sponging miR-1290.4
351118442022SPARCL1 Is a Novel Prognostic Biomarker and Correlates with Tumor Microenvironment in Colorectal Cancer.6
351362092022The KDM6A-SPARCL1 axis blocks metastasis and regulates the tumour microenvironment of gastrointestinal stromal tumours by inhibiting the nuclear translocation of p65.4
355498062022Circular_0086414 induces SPARC like 1 (SPARCL1) production to inhibit esophageal cancer cell proliferation, invasion and glycolysis and induce cell apoptosis by sponging miR-1290.4
335350262021Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges.12
340338692021Characterization of Hevin (SPARCL1) Immunoreactivity in Postmortem Human Brain Homogenates.2
344355122021SPARCL1 exhibits different expressions in left- and right-sided colon cancer and is downregulated via DNA methylation.2

Citation

Dessen P

SPARCL1 (SPARC like 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42370/sparcl1-(sparc-like-1)