Identity
HGNC
LOCATION
5q31.2
LOCUSID
ALIAS
SPOCK,TESTICAN,TIC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6695
MIM: 602264
HGNC: 11251
Ensembl: ENSG00000152377
Variants:
dbSNP: 6695
ClinVar: 6695
TCGA: ENSG00000152377
COSMIC: SPOCK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000152377 | ENST00000282223 | A0A0A0MQX7 |
| ENSG00000152377 | ENST00000394945 | Q08629 |
| ENSG00000152377 | ENST00000505690 | D6RB21 |
| ENSG00000152377 | ENST00000510689 | D6RAM7 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33090888 | 2023 | Knockdown of Long Noncoding RNA Urothelial Carcinoma-Associated 1 Represses Gallbladder Cancer Advancement by Regulating SPOCK1 Expression Through Sponging miR-613. | 2 |
| 36611136 | 2023 | SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer. | 3 |
| 36766694 | 2023 | Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition. | 2 |
| 38087364 | 2023 | SPOCK1, as a potential prognostic and therapeutic biomarker for lung adenocarcinoma, is associated with epithelial-mesenchymal transition and immune evasion. | 0 |
| 33090888 | 2023 | Knockdown of Long Noncoding RNA Urothelial Carcinoma-Associated 1 Represses Gallbladder Cancer Advancement by Regulating SPOCK1 Expression Through Sponging miR-613. | 2 |
| 36611136 | 2023 | SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer. | 3 |
| 36766694 | 2023 | Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition. | 2 |
| 38087364 | 2023 | SPOCK1, as a potential prognostic and therapeutic biomarker for lung adenocarcinoma, is associated with epithelial-mesenchymal transition and immune evasion. | 0 |
| 34855159 | 2022 | SPOCK1 promotes metastasis in pancreatic cancer via NF-κB-dependent epithelial-mesenchymal transition by interacting with IκB-α. | 11 |
| 35221802 | 2022 | Expression and Potential Prognostic Value of SOX9, MCL-1 and SPOCK1 in Gastric Adenocarcinoma. | 1 |
| 35462225 | 2022 | SPOCK1 silencing decreases 5-FU resistance through PRRX1 in colorectal cancer. | 1 |
| 34855159 | 2022 | SPOCK1 promotes metastasis in pancreatic cancer via NF-κB-dependent epithelial-mesenchymal transition by interacting with IκB-α. | 11 |
| 35221802 | 2022 | Expression and Potential Prognostic Value of SOX9, MCL-1 and SPOCK1 in Gastric Adenocarcinoma. | 1 |
| 35462225 | 2022 | SPOCK1 silencing decreases 5-FU resistance through PRRX1 in colorectal cancer. | 1 |
| 33517826 | 2021 | Long non-coding RNA TTN antisense RNA 1 facilitates hepatocellular carcinoma progression via regulating miR-139-5p/SPOCK1 axis. | 17 |
Citation
Dessen P
SPOCK1 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42376/spock1-(sparc-(osteonectin)-cwcv-and-kazal-like-domains-proteoglycan-1)
