Identity
HGNC
LOCATION
13q31.1
LOCUSID
ALIAS
IGAN3,hSPRY2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10253
MIM: 602466
HGNC: 11270
Ensembl: ENSG00000136158
Variants:
dbSNP: 10253
ClinVar: 10253
TCGA: ENSG00000136158
COSMIC: SPRY2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136158 | ENST00000377102 | O43597 |
| ENSG00000136158 | ENST00000377104 | O43597 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37824392 | 2024 | The ceRNA Mechanism of lncRNA MEG3/miR-21-5p/SPRY2 in Cell Proliferation and Apoptosis in Bladder Cancer. | 0 |
| 37824392 | 2024 | The ceRNA Mechanism of lncRNA MEG3/miR-21-5p/SPRY2 in Cell Proliferation and Apoptosis in Bladder Cancer. | 0 |
| 37507768 | 2023 | Loss of SPRY2 contributes to cancer-associated fibroblasts activation and promotes breast cancer development. | 0 |
| 37700432 | 2023 | The Prognostic and Functional Impact of Sprouty 2 Expression in Non-small Cell Lung Cancer. | 0 |
| 37507768 | 2023 | Loss of SPRY2 contributes to cancer-associated fibroblasts activation and promotes breast cancer development. | 0 |
| 37700432 | 2023 | The Prognostic and Functional Impact of Sprouty 2 Expression in Non-small Cell Lung Cancer. | 0 |
| 34847450 | 2022 | SNHG12 regulates biological behaviors of ox-LDL-induced HA-VSMCs through upregulation of SPRY2 and NUB1. | 2 |
| 34847450 | 2022 | SNHG12 regulates biological behaviors of ox-LDL-induced HA-VSMCs through upregulation of SPRY2 and NUB1. | 2 |
| 32789554 | 2021 | Sprouty2 Inhibits Migration and Invasion of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Down-regulating ATF2 Expression and Phosphorylation. | 6 |
| 33547321 | 2021 | Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33. | 20 |
| 33684096 | 2021 | Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases. | 3 |
| 33760112 | 2021 | MicroRNA-124 facilitates lens epithelial cell apoptosis by inhibiting SPRY2 and MMP-2. | 5 |
| 34685612 | 2021 | Epigenetic DNA Modifications Upregulate SPRY2 in Human Colorectal Cancers. | 2 |
| 32789554 | 2021 | Sprouty2 Inhibits Migration and Invasion of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Down-regulating ATF2 Expression and Phosphorylation. | 6 |
| 33547321 | 2021 | Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33. | 20 |
Citation
Dessen P
SPRY2 (sprouty RTK signaling antagonist 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42381/spry2-(sprouty-rtk-signaling-antagonist-2)
