ST18 (ST18 C2H2C-type zinc finger transcription factor)

2003-06-01  

Identity

HGNC
ST18
LOCATION
8q11.23
LOCUSID
9705
ALIAS
NZF-3,NZF3,ZC2H2C3,ZC2HC10,ZNF387
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9705
MIM: 617155
HGNC: 18695
Ensembl: ENSG00000147488

Variants:

dbSNP: 9705
ClinVar: 9705
TCGA: ENSG00000147488
COSMIC: ST18

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147488ENST00000276480O60284
ENSG00000147488ENST00000517580E5RHS3
ENSG00000147488ENST00000519118E5RK88
ENSG00000147488ENST00000521582E5RID0
ENSG00000147488ENST00000521824E5RHY1
ENSG00000147488ENST00000522251E5RFE8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
154898932004ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.29
186764042008The transcription factor ST18 regulates proapoptotic and proinflammatory gene expression in fibroblasts.23
224373162012Population-specific association between a polymorphic variant in ST18, encoding a pro-apoptotic molecule, and pemphigus vulgaris.22
271487412016Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene.13
245098572014A critical role for the neural zinc factor ST18 in pancreatic β-cell apoptosis.7
235053052013Genotype-phenotype analysis of SNPs associated with primary angle closure glaucoma (rs1015213, rs3753841 and rs11024102) and ocular biometry in the EPIC-Norfolk Eye Study.5
238473142013Association study in a South Indian population supports rs1015213 as a risk factor for primary angle closure.3
293109652018Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci in Patients with Early Stages of Angle-Closure Disease.3
301924162018The association between ST18 gene polymorphism and severe pemphigus disease among Iranian population.3

Citation

Dessen P

ST18 (ST18 C2H2C-type zinc finger transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42419/st18-(st18-c2h2c-type-zinc-finger-transcription-factor)