DENND2B (DENN domain containing 2B)

2003-02-01  

Identity

HGNC
DENND2B
LOCATION
11p15.4
LOCUSID
6764
ALIAS
HTS1,ST5,p126
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6764
MIM: 140750
HGNC: 11350
Ensembl: ENSG00000166444

Variants:

dbSNP: 6764
ClinVar: 6764
TCGA: ENSG00000166444
COSMIC: DENND2B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166444ENST00000313726P78524
ENSG00000166444ENST00000524757E9PRS6
ENSG00000166444ENST00000525169E9PM32
ENSG00000166444ENST00000526057E9PPL2
ENSG00000166444ENST00000526062H0YD60
ENSG00000166444ENST00000526099B4DDL8
ENSG00000166444ENST00000526126E9PI67
ENSG00000166444ENST00000526155E9PME1
ENSG00000166444ENST00000526241E9PLH6
ENSG00000166444ENST00000526757P78524
ENSG00000166444ENST00000526828E9PJP0
ENSG00000166444ENST00000527347E9PK36
ENSG00000166444ENST00000527392E9PLD7
ENSG00000166444ENST00000527473E9PLB6
ENSG00000166444ENST00000527510E9PNM8
ENSG00000166444ENST00000527516E9PII1
ENSG00000166444ENST00000527930E9PM84
ENSG00000166444ENST00000528196E9PKN3
ENSG00000166444ENST00000528523E9PJY5
ENSG00000166444ENST00000528527E9PKM1
ENSG00000166444ENST00000530338H0YE59
ENSG00000166444ENST00000530438P78524
ENSG00000166444ENST00000530580E9PQA9
ENSG00000166444ENST00000530593E9PNX7
ENSG00000166444ENST00000530938E9PI72
ENSG00000166444ENST00000530959E9PMP1
ENSG00000166444ENST00000530991P78524
ENSG00000166444ENST00000531060H0YDL0
ENSG00000166444ENST00000531093E9PI58
ENSG00000166444ENST00000531578E9PQM5
ENSG00000166444ENST00000532734E9PJC3
ENSG00000166444ENST00000533016E9PQU6
ENSG00000166444ENST00000533020E9PKE0
ENSG00000166444ENST00000533225E9PKV3
ENSG00000166444ENST00000533471E9PI72
ENSG00000166444ENST00000533580E9PLR2
ENSG00000166444ENST00000533681E9PMJ9
ENSG00000166444ENST00000534127P78524
ENSG00000166444ENST00000534248E9PN93
ENSG00000166444ENST00000534278E9PLH5
ENSG00000166444ENST00000534665E9PPS6
ENSG00000166444ENST00000626808E9PJC3

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198

References

Pubmed IDYearTitleCitations
374542962023DENND2B activates Rab35 at the intercellular bridge, regulating cytokinetic abscission and tetraploidy.2
374542962023DENND2B activates Rab35 at the intercellular bridge, regulating cytokinetic abscission and tetraploidy.2
317077782019ST5 Positively Regulates Osteoclastogenesis via Src/Syk/calcium Signaling Pathways.3
317077782019ST5 Positively Regulates Osteoclastogenesis via Src/Syk/calcium Signaling Pathways.3
290304802017Intersectin-s interaction with DENND2B facilitates recycling of epidermal growth factor receptor.8
290304802017Intersectin-s interaction with DENND2B facilitates recycling of epidermal growth factor receptor.8
257134152015DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.50
257134152015DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.50
198435052010Disruption of ST5 is associated with mental retardation and multiple congenital anomalies.5
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
198435052010Disruption of ST5 is associated with mental retardation and multiple congenital anomalies.5
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

DENND2B (DENN domain containing 2B)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42423/dennd2b-(denn-domain-containing-2b)