Identity
HGNC
LOCATION
12q13.3
LOCUSID
ALIAS
D12S1644,IL-4-STAT,STAT6B,STAT6C
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6778
MIM: 601512
HGNC: 11368
Ensembl: ENSG00000166888
Variants:
dbSNP: 6778
ClinVar: 6778
TCGA: ENSG00000166888
COSMIC: STAT6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38238227 | 2024 | Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond. | 0 |
| 38285120 | 2024 | STAT6 mutations enriched at diffuse large B-cell lymphoma relapse reshape the tumor microenvironment. | 0 |
| 38459596 | 2024 | Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p/STAT6 axis to promote gastric cancer progression. | 2 |
| 38238227 | 2024 | Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond. | 0 |
| 38285120 | 2024 | STAT6 mutations enriched at diffuse large B-cell lymphoma relapse reshape the tumor microenvironment. | 0 |
| 38459596 | 2024 | Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p/STAT6 axis to promote gastric cancer progression. | 2 |
| 35918104 | 2023 | Vitamin D receptor and STAT6 interactome governs oesophageal epithelial barrier responses to IL-13 signalling. | 2 |
| 36216080 | 2023 | A germline STAT6 gain-of-function variant is associated with early-onset allergies. | 11 |
| 36757802 | 2023 | IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation. | 7 |
| 36884218 | 2023 | Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease. | 19 |
| 37043379 | 2023 | Signal Transducer and Activator of Transcription 6 Changes and Protein Frustration by Single Amino Acid Substitutions: Implications for Cancer Progression. | 0 |
| 37068104 | 2023 | ROP16-mediated activation of STAT6 enhances cyst development of type III Toxoplasma gondii in neurons. | 2 |
| 37106040 | 2023 | Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of T(H)9 cells to promote allergic inflammation. | 1 |
| 37196636 | 2023 | Learning while treating: Gain-of-function STAT6 variants in severe allergic disease. | 1 |
| 37316763 | 2023 | Autosomal Dominant STAT6 Gain of Function Causes Severe Atopy Associated with Lymphoma. | 4 |
Citation
Dessen P
STAT6 (signal transducer and activator of transcription 6)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42432
