Identity
HGNC
LOCATION
10q24.32
LOCUSID
ALIAS
JBTS32,PRO1280,SUFUH,SUFUXL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51684
MIM: 607035
HGNC: 16466
Ensembl: ENSG00000107882
Variants:
dbSNP: 51684
ClinVar: 51684
TCGA: ENSG00000107882
COSMIC: SUFU
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107882 | ENST00000369899 | Q9UMX1 |
| ENSG00000107882 | ENST00000369902 | Q9UMX1 |
| ENSG00000107882 | ENST00000423559 | Q9UMX1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36524356 | 2023 | WNT5A, β‑catenin and SUFU expression patterns, and the significance of microRNA deregulation in placentas with intrauterine growth restriction. | 1 |
| 36524356 | 2023 | WNT5A, β‑catenin and SUFU expression patterns, and the significance of microRNA deregulation in placentas with intrauterine growth restriction. | 1 |
| 35831023 | 2022 | ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1. | 6 |
| 35831023 | 2022 | ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1. | 6 |
| 33024317 | 2021 | Heterozygous truncating variants in SUFU cause congenital ocular motor apraxia. | 7 |
| 33893086 | 2021 | Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblastoma. | 1 |
| 34260378 | 2021 | Sufu negatively regulates both initiations of centrosome duplication and DNA replication. | 2 |
| 33024317 | 2021 | Heterozygous truncating variants in SUFU cause congenital ocular motor apraxia. | 7 |
| 33893086 | 2021 | Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblastoma. | 1 |
| 34260378 | 2021 | Sufu negatively regulates both initiations of centrosome duplication and DNA replication. | 2 |
| 33017570 | 2020 | SUFU mediates EMT and Wnt/β-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer. | 10 |
| 33017570 | 2020 | SUFU mediates EMT and Wnt/β-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer. | 10 |
| 30554998 | 2019 | Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma. | 27 |
| 31127025 | 2019 | LIFR-AS1 modulates Sufu to inhibit cell proliferation and migration by miR-197-3p in breast cancer. | 24 |
| 30554998 | 2019 | Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma. | 27 |
Citation
Dessen P
SUFU (SUFU negative regulator of hedgehog signaling)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42447/sufu-(sufu-negative-regulator-of-hedgehog-signaling)
