Identity
HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
SPT5,SPT5H,Tat-CT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6829
MIM: 602102
HGNC: 11469
Ensembl: ENSG00000196235
Variants:
dbSNP: 6829
ClinVar: 6829
TCGA: ENSG00000196235
COSMIC: SUPT5H
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38641822 | 2024 | RBM22 regulates RNA polymerase II 5' pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5. | 0 |
| 38641822 | 2024 | RBM22 regulates RNA polymerase II 5' pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5. | 0 |
| 36054783 | 2023 | A stepwise haematological screening and whole-exome sequencing reveal multiple mutations from SUPT5H causing an elevation of Hb A(2) from a cohort of 47336 individuals. | 2 |
| 36054783 | 2023 | A stepwise haematological screening and whole-exome sequencing reveal multiple mutations from SUPT5H causing an elevation of Hb A(2) from a cohort of 47336 individuals. | 2 |
| 35325203 | 2022 | ZWC complex-mediated SPT5 phosphorylation suppresses divergent antisense RNA transcription at active gene promoters. | 7 |
| 35325203 | 2022 | ZWC complex-mediated SPT5 phosphorylation suppresses divergent antisense RNA transcription at active gene promoters. | 7 |
| 33333262 | 2021 | CRISPRi-mediated depletion of Spt4 and Spt5 reveals a role for DSIF in the control of HIV latency. | 4 |
| 34480849 | 2021 | SPT5 stabilization of promoter-proximal RNA polymerase II. | 32 |
| 34534457 | 2021 | SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape. | 36 |
| 33333262 | 2021 | CRISPRi-mediated depletion of Spt4 and Spt5 reveals a role for DSIF in the control of HIV latency. | 4 |
| 34480849 | 2021 | SPT5 stabilization of promoter-proximal RNA polymerase II. | 32 |
| 34534457 | 2021 | SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape. | 36 |
| 32961044 | 2020 | SUPT5H Post-Transcriptional Silencing Modulates PIN1 Expression, Inhibits Tumorigenicity, and Induces Apoptosis of Human Breast Cancer Cells. | 6 |
| 32961044 | 2020 | SUPT5H Post-Transcriptional Silencing Modulates PIN1 Expression, Inhibits Tumorigenicity, and Induces Apoptosis of Human Breast Cancer Cells. | 6 |
| 30928206 | 2019 | MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. | 58 |
Citation
Dessen P
SUPT5H (SPT5 homolog, DSIF elongation factor subunit)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42453/supt5h-(spt5-homolog-dsif-elongation-factor-subunit)
