TACSTD2 (tumor associated calcium signal transducer 2)

2003-05-01  

Identity

HGNC
LOCATION
1p32.1
LOCUSID
ALIAS
EGP-1,EGP1,GA733-1,GA7331,GP50,M1S1,TROP2
FUSION GENES

Other Information

Locus ID:

NCBI: 4070
MIM: 137290
HGNC: 11530
Ensembl: ENSG00000184292

Variants:

dbSNP: 4070
ClinVar: 4070
TCGA: ENSG00000184292
COSMIC: TACSTD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184292ENST00000371225P09758

Expression (GTEx)

0
500
1000
1500

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380480582024TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer.0
380733792024Diagnostic and prognostic utility of TROP-2, SLP-2, and CXCL12 expression in papillary thyroid carcinoma.0
381962022024Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts.2
383025032024DNA demethylation and tri-methylation of H3K4 at the TACSTD2 promoter are complementary players for TROP2 regulation in colorectal cancer cells.0
386855072024TROP2 promotes PINK1-mediated mitophagy and apoptosis to accelerate the progression of senile chronic obstructive pulmonary disease by up-regulating DRP1 expression.0
380480582024TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer.0
380733792024Diagnostic and prognostic utility of TROP-2, SLP-2, and CXCL12 expression in papillary thyroid carcinoma.0
381962022024Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts.2
383025032024DNA demethylation and tri-methylation of H3K4 at the TACSTD2 promoter are complementary players for TROP2 regulation in colorectal cancer cells.0
386855072024TROP2 promotes PINK1-mediated mitophagy and apoptosis to accelerate the progression of senile chronic obstructive pulmonary disease by up-regulating DRP1 expression.0
367597212023Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for the right population for drugs' development.4
370675482023TROP-2 is widely expressed in vulvar squamous cell carcinoma and represents a potential new therapeutic target.0
371214442023Targeting Trop-2 in cancer: Recent research progress and clinical application.6
372682802023TROP2 translation mediated by dual m(6)A/m(7)G RNA modifications promotes bladder cancer development.2
373800812023Trophoblast cell surface antigen-2 phosphorylation triggered by binding of galectin-3 drives metastasis through down-regulation of E-cadherin.2

Citation

Dessen P

TACSTD2 (tumor associated calcium signal transducer 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42460/haematological-explorer/case-report-explorer/hgnc