SERINC3 (serine incorporator 3)

2003-02-01  

Identity

HGNC
LOCATION
20q13.12
LOCUSID
ALIAS
AIGP1,DIFF33,SBBI99,TDE,TDE1,TMS-1
FUSION GENES

Other Information

Locus ID:

NCBI: 10955
MIM: 607165
HGNC: 11699
Ensembl: ENSG00000132824

Variants:

dbSNP: 10955
ClinVar: 10955
TCGA: ENSG00000132824
COSMIC: SERINC3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132824ENST00000255175Q13530
ENSG00000132824ENST00000342374Q13530
ENSG00000132824ENST00000411544Q5H936

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Amino acid synthesis and interconversion (transamination)REACTOMER-HSA-70614
Serine biosynthesisREACTOMER-HSA-977347

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
264167332015SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef.140
165474972006Human TDE1, a TDE1/TMS family member, inhibits apoptosis in vitro and stimulates in vivo tumorigenesis.12
311863272019Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5.6

Citation

Dessen P

SERINC3 (serine incorporator 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42502/serinc3-(serine-incorporator-3)