TESK1 (testis associated actin remodelling kinase 1)

2003-11-01 Affiliation

Identity

HGNC

TESK1

LOCATION

9p13.3

LOCUSID

7016

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 7016
MIM: 601782
HGNC: 11731
Ensembl: ENSG00000107140

Variants:

dbSNP: 7016
ClinVar: 7016
TCGA: ENSG00000107140
COSMIC: TESK1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000107140	ENST00000336395	Q15569
ENSG00000107140	ENST00000620767	Q15569

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Cell-Cell communication	REACTOME	R-HSA-1500931
Cell junction organization	REACTOME	R-HSA-446728
Cell-extracellular matrix interactions	REACTOME	R-HSA-446353
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	REACTOME	R-HSA-446388

References

Pubmed ID	Year	Title	Citations
29396473	2018	Decreased TESK1-mediated cofilin 1 phosphorylation in the jejunum of IBS-D patients may explain increased female predisposition to epithelial dysfunction.	7
29396473	2018	Decreased TESK1-mediated cofilin 1 phosphorylation in the jejunum of IBS-D patients may explain increased female predisposition to epithelial dysfunction.	7
25849865	2015	Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking.	96
25849865	2015	Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking.	96
20237496	2010	New genetic associations detected in a host response study to hepatitis B vaccine.	37
20237496	2010	New genetic associations detected in a host response study to hepatitis B vaccine.	37
18216281	2008	Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeleton.	29
18216281	2008	Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeleton.	29
15817463	2005	Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin.	21
15817463	2005	Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin.	21

Citation

Dessen P

TESK1 (testis associated actin remodelling kinase 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/42525/cancer-prone-explorer/case-report-explorer/welcome