TGFB1I1 (transforming growth factor beta 1 induced transcript 1)

2003-02-01  

Identity

HGNC
TGFB1I1
LOCATION
16p11.2
LOCUSID
7041
ALIAS
ARA55,HIC-5,HIC5,TSC-5

Other Information

Locus ID:

NCBI: 7041
MIM: 602353
HGNC: 11767
Ensembl: ENSG00000140682

Variants:

dbSNP: 7041
ClinVar: 7041
TCGA: ENSG00000140682
COSMIC: TGFB1I1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140682ENST00000361773O43294
ENSG00000140682ENST00000361773A0A024QZE7
ENSG00000140682ENST00000394858O43294
ENSG00000140682ENST00000394858A0A024QZE7
ENSG00000140682ENST00000394863O43294
ENSG00000140682ENST00000562566H3BS04
ENSG00000140682ENST00000563712I3L209
ENSG00000140682ENST00000564804H3BN49
ENSG00000140682ENST00000565360H3BQC4
ENSG00000140682ENST00000565454H3BSN4
ENSG00000140682ENST00000567066H3BRP2
ENSG00000140682ENST00000567607O43294
ENSG00000140682ENST00000567607A0A024QZE7

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381598472024Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDEC.0
381802992024TGFB1I1 promotes cell proliferation and migration in urothelial carcinoma.0
381598472024Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDEC.0
381802992024TGFB1I1 promotes cell proliferation and migration in urothelial carcinoma.0
316831792020Hic-5 in pancreatic stellate cells affects proliferation, apoptosis, migration, invasion of pancreatic cancer cells and postoperative survival time of pancreatic cancer.11
324422722020Increased expression of the transforming growth factor β-inducible gene HIC-5 in systemic sclerosis skin and fibroblasts: a novel antifibrotic therapeutic target.2
327060672020TGFβ1I1 suppressed cell migration and invasion in colorectal cancer by inhibiting the TGF-β pathway and EMT progress.4
328593682020Paxillin family of focal adhesion adaptor proteins and regulation of cancer cell invasion.18
333109722020Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.21
316831792020Hic-5 in pancreatic stellate cells affects proliferation, apoptosis, migration, invasion of pancreatic cancer cells and postoperative survival time of pancreatic cancer.11
324422722020Increased expression of the transforming growth factor β-inducible gene HIC-5 in systemic sclerosis skin and fibroblasts: a novel antifibrotic therapeutic target.2
327060672020TGFβ1I1 suppressed cell migration and invasion in colorectal cancer by inhibiting the TGF-β pathway and EMT progress.4
328593682020Paxillin family of focal adhesion adaptor proteins and regulation of cancer cell invasion.18
333109722020Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.21
302819032019A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in RAS-activated cancer cells.30

Citation

Dessen P

TGFB1I1 (transforming growth factor beta 1 induced transcript 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42535/tgfb1i1-(transforming-growth-factor-beta-1-induced-transcript-1)