TIMM17A (translocase of inner mitochondrial membrane 17A)

2003-06-01  

Identity

HGNC
TIMM17A
LOCATION
1q32.1
LOCUSID
10440
ALIAS
TIM17,TIM17A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10440
MIM: 605057
HGNC: 17315
Ensembl: ENSG00000134375

Variants:

dbSNP: 10440
ClinVar: 10440
TCGA: ENSG00000134375
COSMIC: TIMM17A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134375ENST00000367287Q99595

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Mitochondrial protein importREACTOMER-HSA-1268020

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386324672024TIMM17A overexpression in lung adenocarcinoma and its association with prognosis.0
386324672024TIMM17A overexpression in lung adenocarcinoma and its association with prognosis.0
375277802023Central role of Tim17 in mitochondrial presequence protein translocation.4
375277802023Central role of Tim17 in mitochondrial presequence protein translocation.4
332974902020Tim17 Updates: A Comprehensive Review of an Ancient Mitochondrial Protein Translocator.10
332974902020Tim17 Updates: A Comprehensive Review of an Ancient Mitochondrial Protein Translocator.10
313448552019LncRNA NEAT1 Silenced miR-133b Promotes Migration and Invasion of Breast Cancer Cells.36
313448552019LncRNA NEAT1 Silenced miR-133b Promotes Migration and Invasion of Breast Cancer Cells.36
269770202016The Impact of TIMM17A on Aggressiveness of Human Breast Cancer Cells.6
269770202016The Impact of TIMM17A on Aggressiveness of Human Breast Cancer Cells.6
209727412012High TIMM17A expression is associated with adverse pathological and clinical outcomes in human breast cancer.20
209727412012High TIMM17A expression is associated with adverse pathological and clinical outcomes in human breast cancer.20
201986622010Quantitative proteomics study of breast cancer cell lines isolated from a single patient: discovery of TIMM17A as a marker for breast cancer.28
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
201986622010Quantitative proteomics study of breast cancer cell lines isolated from a single patient: discovery of TIMM17A as a marker for breast cancer.28

Citation

Dessen P

TIMM17A (translocase of inner mitochondrial membrane 17A)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42564/timm17a-(translocase-of-inner-mitochondrial-membrane-17a)