Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26277
MIM: 604319
HGNC: 11824
Ensembl: ENSG00000092330
Variants:
dbSNP: 26277
ClinVar: 26277
TCGA: ENSG00000092330
COSMIC: TINF2
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35590014 | 2023 | Truncating TINF2 p.Tyr312Ter variant and inherited breast cancer susceptibility. | 1 |
| 36651296 | 2023 | Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres. | 3 |
| 37611825 | 2023 | eIF3i promotes colorectal cancer cell survival via augmenting PHGDH translation. | 2 |
| 37646013 | 2023 | TINF2 is a major susceptibility gene in Danish patients with multiple primary melanoma. | 2 |
| 35590014 | 2023 | Truncating TINF2 p.Tyr312Ter variant and inherited breast cancer susceptibility. | 1 |
| 36651296 | 2023 | Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres. | 3 |
| 37611825 | 2023 | eIF3i promotes colorectal cancer cell survival via augmenting PHGDH translation. | 2 |
| 37646013 | 2023 | TINF2 is a major susceptibility gene in Danish patients with multiple primary melanoma. | 2 |
| 34403696 | 2021 | Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA. | 5 |
| 34479523 | 2021 | Pulmonary fibrosis in dyskeratosis congenita: a case report with a PRISMA-compliant systematic review. | 8 |
| 34403696 | 2021 | Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA. | 5 |
| 34479523 | 2021 | Pulmonary fibrosis in dyskeratosis congenita: a case report with a PRISMA-compliant systematic review. | 8 |
| 31928178 | 2020 | A Truncating Germline Mutation of TINF2 in Individuals with Thyroid Cancer or Melanoma Results in Longer Telomeres. | 22 |
| 32910990 | 2020 | Acute depletion of telomerase components DKC1 and NOP10 induces oxidative stress and disrupts ribosomal biogenesis via NPM1 and activation of the P53 pathway. | 8 |
| 33258446 | 2020 | TINF2 is a haploinsufficient tumor suppressor that limits telomere length. | 24 |
Citation
Dessen P
TINF2 (TERF1 interacting nuclear factor 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42575
