Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7083
MIM: 188300
HGNC: 11830
Ensembl: ENSG00000167900
Variants:
dbSNP: 7083
ClinVar: 7083
TCGA: ENSG00000167900
COSMIC: TK1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406956 | fluorouracil | Chemical | VariantAnnotation | not associated | PD | ||
| PA445058 | Neoplasm Metastasis | Disease | VariantAnnotation | not associated | PD | ||
| PA448771 | capecitabine | Chemical | VariantAnnotation | not associated | PD | ||
| PA451954 | zidovudine | Chemical | Pathway | associated | 22960662 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37673047 | 2024 | Clinical Significance of the TK1-Specific Activity in the Early Detection of Ovarian Cancer. | 0 |
| 37673047 | 2024 | Clinical Significance of the TK1-Specific Activity in the Early Detection of Ovarian Cancer. | 0 |
| 36982234 | 2023 | Prediction of Overall Survival by Thymidine Kinase 1 Combined with Prostate-Specific Antigen in Men with Prostate Cancer. | 2 |
| 37715794 | 2023 | Transcription factor Dp-1 knockdown downregulates thymidine kinase 1 expression to protect against proliferation and epithelial-mesenchymal transition in cervical cancer. | 0 |
| 38033034 | 2023 | TK1 expression influences pathogenicity by cell cycle progression, cellular migration, and cellular survival in HCC 1806 breast cancer cells. | 0 |
| 36982234 | 2023 | Prediction of Overall Survival by Thymidine Kinase 1 Combined with Prostate-Specific Antigen in Men with Prostate Cancer. | 2 |
| 37715794 | 2023 | Transcription factor Dp-1 knockdown downregulates thymidine kinase 1 expression to protect against proliferation and epithelial-mesenchymal transition in cervical cancer. | 0 |
| 38033034 | 2023 | TK1 expression influences pathogenicity by cell cycle progression, cellular migration, and cellular survival in HCC 1806 breast cancer cells. | 0 |
| 35220246 | 2022 | Serum Concentration of Thymidine Kinase 1 (TK1) as a Tumor Marker in Soft Tissue Sarcomas. | 0 |
| 35220246 | 2022 | Serum Concentration of Thymidine Kinase 1 (TK1) as a Tumor Marker in Soft Tissue Sarcomas. | 0 |
| 33517301 | 2021 | Elevated Free Triiodothyronine Is Associated With Increased Proliferative Activity in Triple-negative Breast Cancer. | 2 |
| 33517319 | 2021 | Clinical Applicability of the Proliferation Marker Thymidine Kinase 1 in Head and Neck Cancer Patients. | 1 |
| 34521624 | 2021 | Evaluating Serum Thymidine Kinase 1 in Patients with Hormone Receptor-Positive Metastatic Breast Cancer Receiving First-line Endocrine Therapy in the SWOG S0226 Trial. | 5 |
| 33517301 | 2021 | Elevated Free Triiodothyronine Is Associated With Increased Proliferative Activity in Triple-negative Breast Cancer. | 2 |
| 33517319 | 2021 | Clinical Applicability of the Proliferation Marker Thymidine Kinase 1 in Head and Neck Cancer Patients. | 1 |
Citation
Dessen P
TK1 (thymidine kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42576/tk1-(thymidine-kinase-1)
