Identity
HGNC
LOCATION
11q13.3
LOCUSID
ALIAS
DOG1,ORAOV2,TAOS2,TMEM16A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55107
MIM: 610108
HGNC: 21625
Ensembl: ENSG00000131620
Variants:
dbSNP: 55107
ClinVar: 55107
TCGA: ENSG00000131620
COSMIC: ANO1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transmembrane transport of small molecules | REACTOME | R-HSA-382551 |
| Ion channel transport | REACTOME | R-HSA-983712 |
| Stimuli-sensing channels | REACTOME | R-HSA-2672351 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35768554 | 2024 | Function and Regulation of the Calcium-Activated Chloride Channel Anoctamin 1 (TMEM16A). | 2 |
| 38084409 | 2024 | Anoctamin-1 is induced by TGF-β and contributes to lung myofibroblast differentiation. | 0 |
| 38155002 | 2024 | TMEM16A enhances the activity of the Cdc42-NWASP signaling pathway to promote invasion and metastasis in oral squamous cell carcinoma. | 0 |
| 38193301 | 2024 | The TMEM16A channel as a potential therapeutic target in vascular disease. | 0 |
| 38336104 | 2024 | Ano1 regulates embryo transport by modulating intracellular calcium levels in oviduct smooth muscle. | 0 |
| 38352864 | 2024 | High ANO1 expression is a prognostic factor and correlated with an immunosuppressive tumor microenvironment in pancreatic cancer. | 0 |
| 38773164 | 2024 | Promoter hypermethylation as a novel regulator of ANO1 expression and function in prostate cancer bone metastasis. | 0 |
| 39046409 | 2024 | [Expressions of zinc homeostasis proteins, GPR39 and ANO1 mRNA in the sperm of asthenozoospermia patients and their clinical significance]. | 0 |
| 35768554 | 2024 | Function and Regulation of the Calcium-Activated Chloride Channel Anoctamin 1 (TMEM16A). | 2 |
| 38084409 | 2024 | Anoctamin-1 is induced by TGF-β and contributes to lung myofibroblast differentiation. | 0 |
| 38155002 | 2024 | TMEM16A enhances the activity of the Cdc42-NWASP signaling pathway to promote invasion and metastasis in oral squamous cell carcinoma. | 0 |
| 38193301 | 2024 | The TMEM16A channel as a potential therapeutic target in vascular disease. | 0 |
| 38336104 | 2024 | Ano1 regulates embryo transport by modulating intracellular calcium levels in oviduct smooth muscle. | 0 |
| 38352864 | 2024 | High ANO1 expression is a prognostic factor and correlated with an immunosuppressive tumor microenvironment in pancreatic cancer. | 0 |
| 38773164 | 2024 | Promoter hypermethylation as a novel regulator of ANO1 expression and function in prostate cancer bone metastasis. | 0 |
Citation
Dessen P
ANO1 (anoctamin 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42588/ano1-(anoctamin-1)
