Identity
HGNC
LOCATION
1q25.1
LOCUSID
ALIAS
CD134L,CD252,GP34,OX-40L,OX4OL,TNLG2B,TXGP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7292
MIM: 603594
HGNC: 11934
Ensembl: ENSG00000117586
Variants:
dbSNP: 7292
ClinVar: 7292
TCGA: ENSG00000117586
COSMIC: TNFSF4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000117586 | ENST00000281834 | P23510 |
| ENSG00000117586 | ENST00000281834 | A0A024R937 |
| ENSG00000117586 | ENST00000367718 | P23510 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38142184 | 2024 | Differential expression of immune checkpoints (OX40/OX40L and PD-1/PD-L1) in decidua of unexplained recurrent spontaneous abortion women. | 0 |
| 38607026 | 2024 | An OX-Tra'Ordinary Tale: The Role of OX40 and OX40L in Atopic Dermatitis. | 1 |
| 38142184 | 2024 | Differential expression of immune checkpoints (OX40/OX40L and PD-1/PD-L1) in decidua of unexplained recurrent spontaneous abortion women. | 0 |
| 38607026 | 2024 | An OX-Tra'Ordinary Tale: The Role of OX40 and OX40L in Atopic Dermatitis. | 1 |
| 33161796 | 2022 | Association of TNFSF4 Gene Polymorphisms and Plasma TNFSF4 Level with Risk of Systemic Lupus Erythematosus in a Chinese Population. | 0 |
| 34282497 | 2022 | Expansion of cytotoxic natural killer cells in multiple myeloma patients using K562 cells expressing OX40 ligand and membrane-bound IL-18 and IL-21. | 13 |
| 35078374 | 2022 | PCSK9 Suppresses M2-Like Tumor-Associated Macrophage Polarization by Regulating the Secretion of OX40L from Hepatocellular Carcinoma Cells. | 6 |
| 35265719 | 2022 | Clinical Significance of OX40 and OX40 Ligand in the Peripheral Blood of Patients with Myasthenia Gravis. | 0 |
| 35835012 | 2022 | TNFSF4 is a risk factor for rheumatoid arthritis but not for primary Sjögren's syndrome in the Mexican population. | 0 |
| 33161796 | 2022 | Association of TNFSF4 Gene Polymorphisms and Plasma TNFSF4 Level with Risk of Systemic Lupus Erythematosus in a Chinese Population. | 0 |
| 34282497 | 2022 | Expansion of cytotoxic natural killer cells in multiple myeloma patients using K562 cells expressing OX40 ligand and membrane-bound IL-18 and IL-21. | 13 |
| 35078374 | 2022 | PCSK9 Suppresses M2-Like Tumor-Associated Macrophage Polarization by Regulating the Secretion of OX40L from Hepatocellular Carcinoma Cells. | 6 |
| 35265719 | 2022 | Clinical Significance of OX40 and OX40 Ligand in the Peripheral Blood of Patients with Myasthenia Gravis. | 0 |
| 35835012 | 2022 | TNFSF4 is a risk factor for rheumatoid arthritis but not for primary Sjögren's syndrome in the Mexican population. | 0 |
| 32208776 | 2021 | Associations between TNFSF4 gene polymorphisms (rs2205960 G > A, rs704840 T > G and rs844648 G > A) and susceptibility to autoimmune diseases in Asians: a meta-analysis. | 3 |
Citation
Dessen P
TNFSF4 (TNF superfamily member 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42640/tnfsf4-(tnf-superfamily-member-4)
