Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10043
MIM: 604700
HGNC: 11982
Ensembl: ENSG00000100284
Variants:
dbSNP: 10043
ClinVar: 10043
TCGA: ENSG00000100284
COSMIC: TOM1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30185465 | 2018 | TOM1 Regulates Neuronal Accumulation of Amyloid-β Oligomers by FcγRIIb2 Variant in Alzheimer's Disease. | 17 |
| 30185465 | 2018 | TOM1 Regulates Neuronal Accumulation of Amyloid-β Oligomers by FcγRIIb2 Variant in Alzheimer's Disease. | 17 |
| 27206884 | 2016 | Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease. | 7 |
| 27206884 | 2016 | Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease. | 7 |
| 25588840 | 2015 | TOM1 is a PI5P effector involved in the regulation of endosomal maturation. | 29 |
| 26007630 | 2015 | Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma. | 52 |
| 26320582 | 2015 | Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism. | 14 |
| 25588840 | 2015 | TOM1 is a PI5P effector involved in the regulation of endosomal maturation. | 29 |
| 26007630 | 2015 | Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma. | 52 |
| 26320582 | 2015 | Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism. | 14 |
| 23023224 | 2012 | Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome. | 160 |
| 23023224 | 2012 | Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome. | 160 |
| 20083669 | 2010 | miR-126 is downregulated in cystic fibrosis airway epithelial cells and regulates TOM1 expression. | 88 |
| 20083669 | 2010 | miR-126 is downregulated in cystic fibrosis airway epithelial cells and regulates TOM1 expression. | 88 |
| 17671966 | 2008 | Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1. | 6 |
Citation
Dessen P
TOM1 (target of myb1 membrane trafficking protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42654/tom1-(target-of-myb1-membrane-trafficking-protein)
