TOMM22 (translocase of outer mitochondrial membrane 22)

2003-06-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
1C9-2,MST065,MSTP065,TOM22
FUSION GENES

Other Information

Locus ID:

NCBI: 56993
MIM: 607046
HGNC: 18002
Ensembl: ENSG00000100216

Variants:

dbSNP: 56993
ClinVar: 56993
TCGA: ENSG00000100216
COSMIC: TOMM22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100216ENST00000216034Q9NS69
ENSG00000100216ENST00000216034Q549C5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Mitochondrial protein importREACTOMER-HSA-1268020
MitophagyREACTOMER-HSA-5205647
Pink/Parkin Mediated MitophagyREACTOMER-HSA-5205685

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378780102024Mitochondrial Translocase TOMM22 Is Overexpressed in Pancreatic Cancer and Promotes Aggressive Growth by Modulating Mitochondrial Protein Import and Function.0
378780102024Mitochondrial Translocase TOMM22 Is Overexpressed in Pancreatic Cancer and Promotes Aggressive Growth by Modulating Mitochondrial Protein Import and Function.0
357332572022Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors.17
357332572022Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors.17
275922262017The mitochondrial BK(Ca) channel cardiac interactome reveals BK(Ca) association with the mitochondrial import receptor subunit Tom22, and the adenine nucleotide translocator.12
275922262017The mitochondrial BK(Ca) channel cardiac interactome reveals BK(Ca) association with the mitochondrial import receptor subunit Tom22, and the adenine nucleotide translocator.12
267878392016An Outer Mitochondrial Translocase, Tom22, Is Crucial for Inner Mitochondrial Steroidogenic Regulation in Adrenal and Gonadal Tissues.17
267878392016An Outer Mitochondrial Translocase, Tom22, Is Crucial for Inner Mitochondrial Steroidogenic Regulation in Adrenal and Gonadal Tissues.17
241494402013The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance.60
241494402013The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance.60
221783942012The role of miRNAs and EBV BARTs in NPC.53
221981992012The cytosolic domain of human Tom22 modulates human Bax mitochondrial translocation and conformation in yeast.8
221783942012The role of miRNAs and EBV BARTs in NPC.53
221981992012The cytosolic domain of human Tom22 modulates human Bax mitochondrial translocation and conformation in yeast.8
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20

Citation

Dessen P

TOMM22 (translocase of outer mitochondrial membrane 22)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42656/tomm22-(translocase-of-outer-mitochondrial-membrane-22)