Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8940
MIM: 603582
HGNC: 11993
Ensembl: ENSG00000100038
Variants:
dbSNP: 8940
ClinVar: 8940
TCGA: ENSG00000100038
COSMIC: TOP3B
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35748872 | 2022 | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | 8 |
| 35945419 | 2022 | Structural and biochemical basis for DNA and RNA catalysis by human Topoisomerase 3β. | 6 |
| 35748872 | 2022 | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | 8 |
| 35945419 | 2022 | Structural and biochemical basis for DNA and RNA catalysis by human Topoisomerase 3β. | 6 |
| 32028044 | 2020 | Further evidence of GABRA4 and TOP3B as autism susceptibility genes. | 10 |
| 32735900 | 2020 | Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses. | 19 |
| 33378676 | 2020 | DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks. | 24 |
| 32028044 | 2020 | Further evidence of GABRA4 and TOP3B as autism susceptibility genes. | 10 |
| 32735900 | 2020 | Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses. | 19 |
| 33378676 | 2020 | DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks. | 24 |
| 31795919 | 2019 | Loss of TOP3B leads to increased R-loop formation and genome instability. | 31 |
| 31795919 | 2019 | Loss of TOP3B leads to increased R-loop formation and genome instability. | 31 |
| 29471495 | 2018 | Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization. | 41 |
| 29490292 | 2018 | TOP3B: A Novel Candidate Gene in Juvenile Myoclonic Epilepsy? | 13 |
| 29471495 | 2018 | Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization. | 41 |
Citation
Dessen P
TOP3B (DNA topoisomerase III beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42661/top3b-(dna-topoisomerase-iii-beta)
