Identity
HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
AGS1,CRV,DRN3,HERNS,RVCLS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11277
MIM: 606609
HGNC: 12269
Ensembl: ENSG00000213689
Variants:
dbSNP: 11277
ClinVar: 11277
TCGA: ENSG00000213689
COSMIC: TREX1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38129659 | 2024 | TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. | 0 |
| 38675842 | 2024 | The Expression Levels of TREX1 and IFN-α Are Associated with Immune Reconstitution in HIV-1-Infected Individuals. | 0 |
| 38824133 | 2024 | Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans. | 1 |
| 38926338 | 2024 | MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling. | 0 |
| 38129659 | 2024 | TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. | 0 |
| 38675842 | 2024 | The Expression Levels of TREX1 and IFN-α Are Associated with Immune Reconstitution in HIV-1-Infected Individuals. | 0 |
| 38824133 | 2024 | Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans. | 1 |
| 38926338 | 2024 | MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling. | 0 |
| 36586737 | 2023 | TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients. | 1 |
| 37298611 | 2023 | TREX1 531C/T Polymorphism and Autoantibodies Associated with the Immune Status of HIV-1-Infected Individuals. | 1 |
| 37728706 | 2023 | Association of TREX1 polymorphism with disease progression in human immunodeficiency virus type-1 (HIV-1) infected patients. | 1 |
| 36586737 | 2023 | TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients. | 1 |
| 37298611 | 2023 | TREX1 531C/T Polymorphism and Autoantibodies Associated with the Immune Status of HIV-1-Infected Individuals. | 1 |
| 37728706 | 2023 | Association of TREX1 polymorphism with disease progression in human immunodeficiency virus type-1 (HIV-1) infected patients. | 1 |
| 34400195 | 2022 | Photosensitivity and cGAS-Dependent IFN-1 Activation in Patients with Lupus and TREX1 Deficiency. | 8 |
Citation
Dessen P
TREX1 (three prime repair exonuclease 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/42696/trex1-(three-prime-repair-exonuclease-1)
