Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11219
MIM: 300370
HGNC: 12270
Ensembl: ENSG00000183479
Variants:
dbSNP: 11219
ClinVar: 11219
TCGA: ENSG00000183479
COSMIC: TREX2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38066323 | 2023 | The Human TREX-2 Complex Interacts with Subunits of the ORC Complex. | 0 |
| 38066323 | 2023 | The Human TREX-2 Complex Interacts with Subunits of the ORC Complex. | 0 |
| 32917881 | 2020 | Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway. | 49 |
| 33357432 | 2020 | TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51(K133A). | 6 |
| 32917881 | 2020 | Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway. | 49 |
| 33357432 | 2020 | TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51(K133A). | 6 |
| 31053176 | 2019 | DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer. | 15 |
| 31053176 | 2019 | DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer. | 15 |
| 30054449 | 2018 | Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair. | 11 |
| 30054449 | 2018 | Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair. | 11 |
| 26090614 | 2015 | Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis. | 11 |
| 26090614 | 2015 | Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis. | 11 |
| 24896180 | 2014 | BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2. | 292 |
| 24896180 | 2014 | BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2. | 292 |
| 23591820 | 2013 | The human TREX-2 complex is stably associated with the nuclear pore basket. | 62 |
Citation
Dessen P
TREX2 (three prime repair exonuclease 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/42697/trex2
