Identity
HGNC
LOCATION
19q13.43
LOCUSID
ALIAS
KAP1,PPP1R157,RNF96,TF1B,TIF1B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10155
MIM: 601742
HGNC: 16384
Ensembl: ENSG00000130726
Variants:
dbSNP: 10155
ClinVar: 10155
TCGA: ENSG00000130726
COSMIC: TRIM28
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Generic Transcription Pathway | REACTOME | R-HSA-212436 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37522419 | 2024 | Up-regulation of Trim28 in pregnancy-induced hypertension is involved in the injury of human umbilical vein endothelial cells through the p38 signaling pathway. | 0 |
| 37792584 | 2024 | TRIM28 inactivation in epithelial nephroblastoma is frequent and often associated with predisposing TRIM28 germline variants. | 2 |
| 38257816 | 2024 | Functional Analysis of KAP1/TRIM28 Requirements for HIV-1 Transcription Activation. | 0 |
| 38677988 | 2024 | [Expression and prognostic significance of KAP1 gene in malignant pleural mesothelioma]. | 0 |
| 38745192 | 2024 | KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m(6)A reader YTHDC1 protein degradation. | 1 |
| 37522419 | 2024 | Up-regulation of Trim28 in pregnancy-induced hypertension is involved in the injury of human umbilical vein endothelial cells through the p38 signaling pathway. | 0 |
| 37792584 | 2024 | TRIM28 inactivation in epithelial nephroblastoma is frequent and often associated with predisposing TRIM28 germline variants. | 2 |
| 38257816 | 2024 | Functional Analysis of KAP1/TRIM28 Requirements for HIV-1 Transcription Activation. | 0 |
| 38677988 | 2024 | [Expression and prognostic significance of KAP1 gene in malignant pleural mesothelioma]. | 0 |
| 38745192 | 2024 | KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m(6)A reader YTHDC1 protein degradation. | 1 |
| 35467255 | 2023 | CRISPR/Cas9-Mediated Disruption of ZNF543 Gene: An Approach Toward Discovering Its Relation to TRIM28 Gene in Parkinson's Disease. | 1 |
| 36341538 | 2023 | The bromodomain protein TRIM28 controls the balance between growth and invasiveness in melanoma. | 4 |
| 36637424 | 2023 | SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors. | 7 |
| 36935008 | 2023 | TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy. | 9 |
| 36992419 | 2023 | Pregnancy Is Associated with Impaired Transcription of Human Endogenous Retroviruses and of TRIM28 and SETDB1, Particularly in Mothers Affected by Multiple Sclerosis. | 1 |
Citation
Dessen P
TRIM28 (tripartite motif containing 28)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/42700/trim28-(tripartite-motif-containing-28)
