Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7347
MIM: 603090
HGNC: 12515
Ensembl: ENSG00000118939
Variants:
dbSNP: 7347
ClinVar: 7347
TCGA: ENSG00000118939
COSMIC: UCHL3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000118939 | ENST00000377595 | P15374 |
| ENSG00000118939 | ENST00000377595 | A0A140VJZ4 |
| ENSG00000118939 | ENST00000419068 | Q5TBK7 |
| ENSG00000118939 | ENST00000618773 | A0A087WTB8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38092274 | 2024 | UCHL3 inhibits ferroptosis by stabilizing β-catenin and maintains stem-like properties of hepatocellular carcinoma cells. | 0 |
| 38266402 | 2024 | UCHL-3 as a potential biomarker of ovarian cancer. | 2 |
| 38474064 | 2024 | CircMTA2 Drives Gastric Cancer Progression through Suppressing MTA2 Degradation via Interacting with UCHL3. | 0 |
| 38664501 | 2024 | GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer. | 0 |
| 38965582 | 2024 | UCHL3 promotes hepatocellular carcinoma progression by stabilizing EEF1A1 through deubiquitination. | 0 |
| 38092274 | 2024 | UCHL3 inhibits ferroptosis by stabilizing β-catenin and maintains stem-like properties of hepatocellular carcinoma cells. | 0 |
| 38266402 | 2024 | UCHL-3 as a potential biomarker of ovarian cancer. | 2 |
| 38474064 | 2024 | CircMTA2 Drives Gastric Cancer Progression through Suppressing MTA2 Degradation via Interacting with UCHL3. | 0 |
| 38664501 | 2024 | GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer. | 0 |
| 38965582 | 2024 | UCHL3 promotes hepatocellular carcinoma progression by stabilizing EEF1A1 through deubiquitination. | 0 |
| 37524875 | 2023 | The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis. | 0 |
| 37740194 | 2023 | Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression. | 3 |
| 37524875 | 2023 | The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis. | 0 |
| 37740194 | 2023 | Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression. | 3 |
| 35053210 | 2022 | Rational Development and Characterization of a Ubiquitin Variant with Selectivity for Ubiquitin C-Terminal Hydrolase L3. | 3 |
Citation
Dessen P
UCHL3 (ubiquitin C-terminal hydrolase L3)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42762/uchl3-(ubiquitin-c-terminal-hydrolase-l3)
