Identity
HGNC
LOCATION
12q24.11
LOCUSID
ALIAS
DGU,HIGM4,HIGM5,UDG,UNG1,UNG15,UNG2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7374
MIM: 191525
HGNC: 12572
Ensembl: ENSG00000076248
Variants:
dbSNP: 7374
ClinVar: 7374
TCGA: ENSG00000076248
COSMIC: UNG
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36883884 | 2023 | Replication Protein A Enhances Kinetics of Uracil DNA Glycosylase on ssDNA and Across DNA Junctions: Explored with a DNA Repair Complex Produced with SpyCatcher/SpyTag Ligation. | 0 |
| 36890276 | 2023 | Uracil-DNA glycosylase efficiency is modulated by substrate rigidity. | 0 |
| 36883884 | 2023 | Replication Protein A Enhances Kinetics of Uracil DNA Glycosylase on ssDNA and Across DNA Junctions: Explored with a DNA Repair Complex Produced with SpyCatcher/SpyTag Ligation. | 0 |
| 36890276 | 2023 | Uracil-DNA glycosylase efficiency is modulated by substrate rigidity. | 0 |
| 33640758 | 2021 | The N-terminal domain of uracil-DNA glycosylase: Roles for disordered regions. | 4 |
| 34819670 | 2021 | FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation. | 19 |
| 33640758 | 2021 | The N-terminal domain of uracil-DNA glycosylase: Roles for disordered regions. | 4 |
| 34819670 | 2021 | FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation. | 19 |
| 31855846 | 2020 | Macromolecular crowding induces compaction and DNA binding in the disordered N-terminal domain of hUNG2. | 5 |
| 32998246 | 2020 | Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Excision Repair Proteins. | 3 |
| 31855846 | 2020 | Macromolecular crowding induces compaction and DNA binding in the disordered N-terminal domain of hUNG2. | 5 |
| 32998246 | 2020 | Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Excision Repair Proteins. | 3 |
| 30747491 | 2019 | A common SNP in the UNG gene decreases ovarian cancer risk in BRCA2 mutation carriers. | 0 |
| 30838409 | 2019 | Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil. | 14 |
| 31318548 | 2019 | QM/MM Study of the Uracil DNA Glycosylase Reaction Mechanism: A Competition between Asp145 and His148. | 2 |
Citation
Dessen P
UNG (uracil DNA glycosylase)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42767/ung-(uracil-dna-glycosylase)
