Identity
HGNC
LOCATION
10q22.2
LOCUSID
ALIAS
CMD1W,CMH15,HEL114,MV,MVCL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7414
MIM: 193065
HGNC: 12665
Ensembl: ENSG00000035403
Variants:
dbSNP: 7414
ClinVar: 7414
TCGA: ENSG00000035403
COSMIC: VCL
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444552 | Hypertension | Disease | Literature, MultilinkAnnotation | associated | 24560520 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38648767 | 2024 | Effect of Focal Adhesion Kinase and Vinculin Expression on Migration Parameters of Normal and Tumor Epitheliocytes. | 0 |
| 38648767 | 2024 | Effect of Focal Adhesion Kinase and Vinculin Expression on Migration Parameters of Normal and Tumor Epitheliocytes. | 0 |
| 36662163 | 2023 | Serum claudin-5, claudin-11, occludin, vinculin, paxillin, and beta-catenin levels in preschool children with autism spectrum disorder. | 5 |
| 37061858 | 2023 | [No Effect of the p.Arg230His Variant Of The VCL Protein on the Course of the Hypertrophic Cardiomyopathy In Russian Family Carrying The p.Gln1233Ter Pathogenic Variant In The MYBPC3 Gene]. | 0 |
| 37248996 | 2023 | Vinculin Y822 is an important determinant of ligand binding. | 1 |
| 37548861 | 2023 | Heart Failure with Recovered Ejection Fraction in Patients with Vinculin Loss-of-function Variants. | 1 |
| 36662163 | 2023 | Serum claudin-5, claudin-11, occludin, vinculin, paxillin, and beta-catenin levels in preschool children with autism spectrum disorder. | 5 |
| 37061858 | 2023 | [No Effect of the p.Arg230His Variant Of The VCL Protein on the Course of the Hypertrophic Cardiomyopathy In Russian Family Carrying The p.Gln1233Ter Pathogenic Variant In The MYBPC3 Gene]. | 0 |
| 37248996 | 2023 | Vinculin Y822 is an important determinant of ligand binding. | 1 |
| 37548861 | 2023 | Heart Failure with Recovered Ejection Fraction in Patients with Vinculin Loss-of-function Variants. | 1 |
| 36238292 | 2022 | Expression of the phagocytic receptors α(M)β(2) and α(X)β(2) is controlled by RIAM, VASP and Vinculin in neutrophil-differentiated HL-60 cells. | 2 |
| 36238292 | 2022 | Expression of the phagocytic receptors α(M)β(2) and α(X)β(2) is controlled by RIAM, VASP and Vinculin in neutrophil-differentiated HL-60 cells. | 2 |
| 33491343 | 2021 | Loss-of-function or gain-of-function variations in VINCULIN (VCL) are risk factors of human neural tube defects. | 0 |
| 33535187 | 2021 | High expression of vinculin predicts poor prognosis and distant metastasis and associates with influencing tumor-associated NK cell infiltration and epithelial-mesenchymal transition in gastric cancer. | 11 |
| 33710645 | 2021 | Vinculin orchestrates prostate cancer progression by regulating tumor cell invasion, migration, and proliferation. | 6 |
Citation
Dessen P
VCL (vinculin)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42785
