Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7423
MIM: 601398
HGNC: 12681
Ensembl: ENSG00000173511
Variants:
dbSNP: 7423
ClinVar: 7423
TCGA: ENSG00000173511
COSMIC: VEGFB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000173511 | ENST00000309422 | P49765 |
| ENSG00000173511 | ENST00000309422 | Q7LAP4 |
| ENSG00000173511 | ENST00000426086 | P49765 |
| ENSG00000173511 | ENST00000541681 | H0YGB6 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA130232992 | bevacizumab | Chemical | Pathway | associated | 20124951 | ||
| PA166118342 | aflibercept | Chemical | Pathway | associated | 20124951 | ||
| PA28180 | FLT1 | Gene | Pathway | associated | 20124951 | ||
| PA30086 | KDR | Gene | Pathway | associated | 20124951 | ||
| PA31783 | NRP1 | Gene | Pathway | associated | 20124951 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38536659 | 2024 | Sorcin promotes proliferation of hepatocellular carcinoma by regulating VEGFA/B via PI3K pathway. | 1 |
| 38775031 | 2024 | Chondroitin polymerizing factor promotes development and progression of colorectal cancer via facilitating transcription of VEGFB. | 1 |
| 38536659 | 2024 | Sorcin promotes proliferation of hepatocellular carcinoma by regulating VEGFA/B via PI3K pathway. | 1 |
| 38775031 | 2024 | Chondroitin polymerizing factor promotes development and progression of colorectal cancer via facilitating transcription of VEGFB. | 1 |
| 37591843 | 2023 | VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway. | 6 |
| 37591843 | 2023 | VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway. | 6 |
| 34647407 | 2022 | Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin-1. | 2 |
| 35399943 | 2022 | Increased Serum VEGF-B Level Is Associated With Renal Function Impairment in Patients With Type 2 Diabetes. | 3 |
| 34647407 | 2022 | Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin-1. | 2 |
| 35399943 | 2022 | Increased Serum VEGF-B Level Is Associated With Renal Function Impairment in Patients With Type 2 Diabetes. | 3 |
| 33856262 | 2021 | Co-expression of VEGF-B and FLT-1 correlates with malignancy and prognosis of gastric cancer. | 2 |
| 34301821 | 2021 | The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis. | 7 |
| 33856262 | 2021 | Co-expression of VEGF-B and FLT-1 correlates with malignancy and prognosis of gastric cancer. | 2 |
| 34301821 | 2021 | The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis. | 7 |
| 32499505 | 2020 | Molecular docking, synthesis and biological evaluation of Vascular Endothelial Growth Factor (VEGF) B based peptide as antiangiogenic agent targeting the second domain of the Vascular Endothelial Growth Factor Receptor 1 (VEGFR1D2) for anticancer application. | 10 |
Citation
Dessen P
VEGFB (vascular endothelial growth factor B)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42788/vegfb-(vascular-endothelial-growth-factor-b)
