Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7465
MIM: 193525
HGNC: 12761
Ensembl: ENSG00000166483
Variants:
dbSNP: 7465
ClinVar: 7465
TCGA: ENSG00000166483
COSMIC: WEE1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37516591 | 2024 | Circulating RNA ZFR promotes hepatocellular carcinoma cell proliferation and epithelial-mesenchymal transition process through miR-624-3p/WEE1 axis. | 2 |
| 38047473 | 2024 | In silico and structure-based evaluation of deleterious mutations identified in human Chk1, Chk2, and Wee1 protein kinase. | 0 |
| 37516591 | 2024 | Circulating RNA ZFR promotes hepatocellular carcinoma cell proliferation and epithelial-mesenchymal transition process through miR-624-3p/WEE1 axis. | 2 |
| 38047473 | 2024 | In silico and structure-based evaluation of deleterious mutations identified in human Chk1, Chk2, and Wee1 protein kinase. | 0 |
| 36378528 | 2023 | ODF2L acts as a synthetic lethal partner with WEE1 inhibition in epithelial ovarian cancer models. | 1 |
| 37863324 | 2023 | E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma. | 1 |
| 36378528 | 2023 | ODF2L acts as a synthetic lethal partner with WEE1 inhibition in epithelial ovarian cancer models. | 1 |
| 37863324 | 2023 | E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma. | 1 |
| 34664776 | 2022 | Circ-SNAP47 (hsa_circ_0016760) and miR-625-5p are regulators of WEE1 in regulation of chemoresistance, growth and invasion of DDP-tolerant NSCLC cells via ceRNA pathway. | 4 |
| 35045293 | 2022 | WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity. | 22 |
| 35080031 | 2022 | Verbascoside enhances radiosensitivity of hepatocellular carcinoma cells through regulating miR-101-3p/Wee1 axis. | 2 |
| 35127343 | 2022 | miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1. | 3 |
| 35176168 | 2022 | Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFα Resistance in Head and Neck Cancers. | 5 |
| 35315355 | 2022 | WEE1 kinase is a therapeutic vulnerability in CIC-DUX4 undifferentiated sarcoma. | 4 |
| 36165727 | 2022 | Mitotic Checkpoints and the Role of WEE1 Inhibition in Head and Neck Squamous Cell Carcinoma. | 2 |
Citation
Dessen P
WEE1 (WEE1 G2 checkpoint kinase)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42807/wee1-(wee1-g2-checkpoint-kinase)
