ZMAT3 (zinc finger matrin-type 3)

2003-02-01  

Identity

HGNC
LOCATION
3q26.32
LOCUSID
ALIAS
PAG608,WIG-1,WIG1
FUSION GENES

Other Information

Locus ID:

NCBI: 64393
MIM: 606452
HGNC: 29983
Ensembl: ENSG00000172667

Variants:

dbSNP: 64393
ClinVar: 64393
TCGA: ENSG00000172667
COSMIC: ZMAT3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172667ENST00000311417Q9HA38
ENSG00000172667ENST00000414084C9J8H5
ENSG00000172667ENST00000432729Q9HA38
ENSG00000172667ENST00000652290A0A494C120

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
p53 signaling pathwayKEGGko04115
p53 signaling pathwayKEGGhsa04115

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198052232009The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element.39
231581022013HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3.21
244690382014Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ.21
230859872012Wig1 prevents cellular senescence by regulating p21 mRNA decay through control of RISC recruitment.14
168441152006The p53-induced Wig-1 protein binds double-stranded RNAs with structural characteristics of siRNAs and miRNAs.11
185190392008The p53 target protein Wig-1 binds hnRNP A2/B1 and RNA Helicase A via RNA.10
209620822011The alphaherpesvirus US3/ORF66 protein kinases direct phosphorylation of the nuclear matrix protein matrin 3.8
225138722012Wig-1, a novel regulator of N-Myc mRNA and N-Myc-driven tumor growth.6
215597792011Zinc induces cell cycle arrest and apoptosis by upregulation of WIG-1 in esophageal squamous cancer cell line EC109.4
272069832016Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53.2

Citation

Dessen P

ZMAT3 (zinc finger matrin-type 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42812/zmat3-(zinc-finger-matrin-type-3)