ZMAT3 (zinc finger matrin-type 3)

2003-02-01 Affiliation

Identity

HGNC

ZMAT3

LOCATION

3q26.32

LOCUSID

64393

ALIAS

PAG608,WIG-1,WIG1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 64393
MIM: 606452
HGNC: 29983
Ensembl: ENSG00000172667

Variants:

dbSNP: 64393
ClinVar: 64393
TCGA: ENSG00000172667
COSMIC: ZMAT3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000172667	ENST00000311417	Q9HA38
ENSG00000172667	ENST00000414084	C9J8H5
ENSG00000172667	ENST00000432729	Q9HA38
ENSG00000172667	ENST00000652290	A0A494C120

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
p53 signaling pathway	KEGG	ko04115
p53 signaling pathway	KEGG	hsa04115

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
33334821	2021	The p53-induced RNA-binding protein ZMAT3 is a splicing regulator that inhibits the splicing of oncogenic CD44 variants in colorectal carcinoma.	28
34525951	2021	eIF5B regulates the expression of PD-L1 in prostate cancer cells by interacting with Wig1.	3
33334821	2021	The p53-induced RNA-binding protein ZMAT3 is a splicing regulator that inhibits the splicing of oncogenic CD44 variants in colorectal carcinoma.	28
34525951	2021	eIF5B regulates the expression of PD-L1 in prostate cancer cells by interacting with Wig1.	3
33157015	2020	Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.	36
33157015	2020	Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.	36
28472401	2017	WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms.	5
28472401	2017	WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms.	5
27206983	2016	Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53.	7
27206983	2016	Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53.	7
24469038	2014	Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ.	36
25379706	2014	Expression of the p53 target Wig-1 is associated with HPV status and patient survival in cervical carcinoma.	0
24469038	2014	Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ.	36
25379706	2014	Expression of the p53 target Wig-1 is associated with HPV status and patient survival in cervical carcinoma.	0
23158102	2013	HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3.	31

Citation

Dessen P

ZMAT3 (zinc finger matrin-type 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42812/zmat3-(zinc-finger-matrin-type-3)