WNT11 (Wnt family member 11)

2003-12-01  

Identity

HGNC
LOCATION
11q13.5
LOCUSID
ALIAS
HWNT11
FUSION GENES

Other Information

Locus ID:

NCBI: 7481
MIM: 603699
HGNC: 12776
Ensembl: ENSG00000085741

Variants:

dbSNP: 7481
ClinVar: 7481
TCGA: ENSG00000085741
COSMIC: WNT11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000085741ENST00000322563O96014
ENSG00000085741ENST00000621122H8YS97

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
Wnt signaling pathwayKEGGko04310
MelanogenesisKEGGko04916
Basal cell carcinomaKEGGko05217
mTOR signaling pathwayKEGGhsa04150
Wnt signaling pathwayKEGGhsa04310
MelanogenesisKEGGhsa04916
Pathways in cancerKEGGhsa05200
Basal cell carcinomaKEGGhsa05217
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
Proteoglycans in cancerKEGGhsa05205
Proteoglycans in cancerKEGGko05205
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Wnt signalingKEGGhsa_M00677
Wnt signalingKEGGM00677
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Signaling by WntREACTOMER-HSA-195721
WNT ligand biogenesis and traffickingREACTOMER-HSA-3238698
Beta-catenin independent WNT signalingREACTOMER-HSA-3858494
PCP/CE pathwayREACTOMER-HSA-4086400
Ca2+ pathwayREACTOMER-HSA-4086398
Breast cancerKEGGko05224
Breast cancerKEGGhsa05224

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382756092024Gollop-Wolfgang Complex Is Associated with a Monoallelic Variation in WNT11.0
382756092024Gollop-Wolfgang Complex Is Associated with a Monoallelic Variation in WNT11.0
370878022023Inhibition of Wnt11 impairs the osteogenesis and aggravates the inflammatory response of human mesenchymal stem cells under LPS-induced inflammatory condition.0
370878022023Inhibition of Wnt11 impairs the osteogenesis and aggravates the inflammatory response of human mesenchymal stem cells under LPS-induced inflammatory condition.0
341072372021Noncanonical Wnt Signaling Promotes Myofibroblast Differentiation in Pulmonary Fibrosis.11
345647082021Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.11
341072372021Noncanonical Wnt Signaling Promotes Myofibroblast Differentiation in Pulmonary Fibrosis.11
345647082021Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.11
317566732020Left-right asymmetry in palatal rugae is associated with genetic variants in WNT signaling pathway.4
321474242020Aberrant expression of Wnt/β-catenin signaling pathway genes in aggressive malignant gastric gastrointestinal stromal tumors.4
326359832020WNT11 is a direct target of early growth response protein 1.2
331379352020WNT11-Conditioned Medium Promotes Angiogenesis through the Activation of Non-Canonical WNT-PKC-JNK Signaling Pathway.10
317566732020Left-right asymmetry in palatal rugae is associated with genetic variants in WNT signaling pathway.4
321474242020Aberrant expression of Wnt/β-catenin signaling pathway genes in aggressive malignant gastric gastrointestinal stromal tumors.4
326359832020WNT11 is a direct target of early growth response protein 1.2

Citation

Dessen P

WNT11 (Wnt family member 11)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/42818/wnt11-(wnt-family-member-11)