WNT6 (Wnt family member 6)

2003-02-01  

Identity

HGNC
LOCATION
2q35
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 7475
MIM: 604663
HGNC: 12785
Ensembl: ENSG00000115596

Variants:

dbSNP: 7475
ClinVar: 7475
TCGA: ENSG00000115596
COSMIC: WNT6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115596ENST00000233948Q9Y6F9

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
Wnt signaling pathwayKEGGko04310
MelanogenesisKEGGko04916
Basal cell carcinomaKEGGko05217
mTOR signaling pathwayKEGGhsa04150
Wnt signaling pathwayKEGGhsa04310
MelanogenesisKEGGhsa04916
Pathways in cancerKEGGhsa05200
Basal cell carcinomaKEGGhsa05217
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
Proteoglycans in cancerKEGGhsa05205
Proteoglycans in cancerKEGGko05205
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Wnt signalingKEGGhsa_M00677
Wnt signalingKEGGM00677
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Signaling by WntREACTOMER-HSA-195721
WNT ligand biogenesis and traffickingREACTOMER-HSA-3238698
Breast cancerKEGGko05224
Breast cancerKEGGhsa05224

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375666202023The investigation of WNT6 and WNT10A single nucleotide polymorphisms as potential biomarkers for dental pulp calcification in orthodontic patients.2
375666202023The investigation of WNT6 and WNT10A single nucleotide polymorphisms as potential biomarkers for dental pulp calcification in orthodontic patients.2
353006922022Wnt4, Wnt6 and β-catenin expression in human placental tissue - is there a link with first trimester miscarriage? Results from a pilot study.1
356911142022The glycoprotein Wnt6 regulates human dental papilla cells differentiation by canonical Wnt signaling pathway.0
360753272022WNT6 participates in the occurrence and development of ovarian cancer by upregulating/activating the typical Wnt pathway and Notch1 signaling pathway.0
353006922022Wnt4, Wnt6 and β-catenin expression in human placental tissue - is there a link with first trimester miscarriage? Results from a pilot study.1
356911142022The glycoprotein Wnt6 regulates human dental papilla cells differentiation by canonical Wnt signaling pathway.0
360753272022WNT6 participates in the occurrence and development of ovarian cancer by upregulating/activating the typical Wnt pathway and Notch1 signaling pathway.0
346866982021Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells.7
346866982021Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells.7
316180772020Secreted Wnt6 mediates diabetes-associated centrosome amplification via its receptor FZD4.5
319233452020A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis.15
325728842020MiR-566 protects the malignant progression of breast cancer by negatively regulating WNT6.2
316180772020Secreted Wnt6 mediates diabetes-associated centrosome amplification via its receptor FZD4.5
319233452020A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis.15

Citation

Dessen P

WNT6 (Wnt family member 6)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42827/wnt6-(wnt-family-member-6)