Identity
HGNC
LOCATION
1q25.3
LOCUSID
ALIAS
IBGC6,SLC53A1,SYG1,X3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9213
MIM: 605237
HGNC: 12827
Ensembl: ENSG00000143324
Variants:
dbSNP: 9213
ClinVar: 9213
TCGA: ENSG00000143324
COSMIC: XPR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143324 | ENST00000367589 | Q9UBH6 |
| ENSG00000143324 | ENST00000367590 | Q9UBH6 |
| ENSG00000143324 | ENST00000367590 | A0A024R911 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35388387 | 2022 | The miR-4732-5p/XPR1 axis suppresses the invasion, metastasis, and epithelial-mesenchymal transition of lung adenocarcinoma via the PI3K/Akt/GSK3β/Snail pathway. | 4 |
| 35437317 | 2022 | Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. | 18 |
| 35388387 | 2022 | The miR-4732-5p/XPR1 axis suppresses the invasion, metastasis, and epithelial-mesenchymal transition of lung adenocarcinoma via the PI3K/Akt/GSK3β/Snail pathway. | 4 |
| 35437317 | 2022 | Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. | 18 |
| 32725396 | 2021 | The genetic polymorphisms of XPR1 and SCL34A3 are associated with Fanconi syndrome in Chinese patients of tumor-induced osteomalacia. | 0 |
| 32920730 | 2021 | Circ-XPR1 promotes osteosarcoma proliferation through regulating the miR-214-5p/DDX5 axis. | 18 |
| 34117845 | 2021 | Clinical implication of xenotropic and polytropic retrovirus receptor 1 in papillary thyroid carcinoma. | 1 |
| 32725396 | 2021 | The genetic polymorphisms of XPR1 and SCL34A3 are associated with Fanconi syndrome in Chinese patients of tumor-induced osteomalacia. | 0 |
| 32920730 | 2021 | Circ-XPR1 promotes osteosarcoma proliferation through regulating the miR-214-5p/DDX5 axis. | 18 |
| 34117845 | 2021 | Clinical implication of xenotropic and polytropic retrovirus receptor 1 in papillary thyroid carcinoma. | 1 |
| 32019887 | 2020 | Control of XPR1-dependent cellular phosphate efflux by InsP(8) is an exemplar for functionally-exclusive inositol pyrophosphate signaling. | 44 |
| 32393577 | 2020 | Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis. | 27 |
| 32019887 | 2020 | Control of XPR1-dependent cellular phosphate efflux by InsP(8) is an exemplar for functionally-exclusive inositol pyrophosphate signaling. | 44 |
| 32393577 | 2020 | Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis. | 27 |
| 30995931 | 2019 | Xenotropic and polytropic retrovirus receptor 1 (XPR1) promotes progression of tongue squamous cell carcinoma (TSCC) via activation of NF-κB signaling. | 11 |
Citation
Dessen P
XPR1 (xenotropic and polytropic retrovirus receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/42846/xpr1-(xenotropic-and-polytropic-retrovirus-receptor-1)
