DNAJC2 (DnaJ heat shock protein family (Hsp40) member C2)

2003-02-01  

Identity

HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
MPHOSPH11,MPP11,ZRF1,ZUO1
FUSION GENES

Other Information

Locus ID:

NCBI: 27000
MIM: 605502
HGNC: 13192
Ensembl: ENSG00000105821

Variants:

dbSNP: 27000
ClinVar: 27000
TCGA: ENSG00000105821
COSMIC: DNAJC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105821ENST00000249270Q99543
ENSG00000105821ENST00000379257F2Z3N9
ENSG00000105821ENST00000379263Q99543
ENSG00000105821ENST00000412522F2Z3H0
ENSG00000105821ENST00000426036H7C3L7
ENSG00000105821ENST00000454277C9IZ83

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
211791692010Transcriptional activation of polycomb-repressed genes by ZRF1.50
160024682005The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex.48
158025662005Human Mpp11 J protein: ribosome-tethered molecular chaperones are ubiquitous.36
270914462016ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair.16
284025052017DICER and ZRF1 contribute to chromatin decondensation during nucleotide excision repair.15
227331292013ZRF1 controls oncogene-induced senescence through the INK4-ARF locus.11
244492712014Zrf1 is required to establish and maintain neural progenitor identity.11
253617332015Direct interaction between Id1 and Zrf1 controls neural differentiation of embryonic stem cells.9
242926732014ZRF1 controls the retinoic acid pathway and regulates leukemogenic potential in acute myeloid leukemia.7
275994652016On-site remodeling at chromatin: How multiprotein complexes are rebuilt during DNA repair and transcriptional activation.7

Citation

Dessen P

DNAJC2 (DnaJ heat shock protein family (Hsp40) member C2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42886/dnajc2-(dnaj-heat-shock-protein-family-(hsp40)-member-c2)