Identity
HGNC
LOCATION
10p11.22
LOCUSID
ALIAS
HEL-S-61,KINH,KNS,KNS1,UKHC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3799
MIM: 602809
HGNC: 6324
Ensembl: ENSG00000170759
Variants:
dbSNP: 3799
ClinVar: 3799
TCGA: ENSG00000170759
COSMIC: KIF5B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170759 | ENST00000302418 | P33176 |
| ENSG00000170759 | ENST00000302418 | V9HW29 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36018820 | 2023 | Dominantly acting KIF5B variants with pleiotropic cellular consequences cause variable clinical phenotypes. | 3 |
| 36717601 | 2023 | BORC complex specific components and Kinesin-1 mediate autophagy evasion by the autophagy-resistant Mycobacterium tuberculosis Beijing strain. | 0 |
| 37934770 | 2023 | Dominant negative variants in KIF5B cause osteogenesis imperfecta via down regulation of mTOR signaling. | 1 |
| 36018820 | 2023 | Dominantly acting KIF5B variants with pleiotropic cellular consequences cause variable clinical phenotypes. | 3 |
| 36717601 | 2023 | BORC complex specific components and Kinesin-1 mediate autophagy evasion by the autophagy-resistant Mycobacterium tuberculosis Beijing strain. | 0 |
| 37934770 | 2023 | Dominant negative variants in KIF5B cause osteogenesis imperfecta via down regulation of mTOR signaling. | 1 |
| 34482333 | 2022 | Distinct Clinicopathologic Features and Possible Pathogenesis of Localized ALK-positive Histiocytosis of the Breast. | 5 |
| 34883065 | 2022 | Motor usage imprints microtubule stability along the shaft. | 17 |
| 35050657 | 2022 | Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein MAP7. | 38 |
| 35342932 | 2022 | De novo heterozygous variants in KIF5B cause kyphomelic dysplasia. | 4 |
| 35649356 | 2022 | Synergistic autoinhibition and activation mechanisms control kinesin-1 motor activity. | 14 |
| 35829703 | 2022 | JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport. | 18 |
| 36002889 | 2022 | Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from "first contact" interactions in the tumor microenvironment. | 7 |
| 34482333 | 2022 | Distinct Clinicopathologic Features and Possible Pathogenesis of Localized ALK-positive Histiocytosis of the Breast. | 5 |
| 34883065 | 2022 | Motor usage imprints microtubule stability along the shaft. | 17 |
Citation
Dessen P
KIF5B (kinesin family member 5B)
Atlas Genet Cytogenet Oncol Haematol. 2006-12-01
Online version: http://atlasgeneticsoncology.org/gene/42894
