Identity
HGNC
LOCATION
14q23.1
LOCUSID
ALIAS
PKC-L,PKCL,PRKCL,nPKC-eta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5583
MIM: 605437
HGNC: 9403
Ensembl: ENSG00000027075
Variants:
dbSNP: 5583
ClinVar: 5583
TCGA: ENSG00000027075
COSMIC: PRKCH
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128394595 | PLCH1 | Gene | Pathway | associated | |||
| PA134875646 | PLCZ1 | Gene | Pathway | associated | |||
| PA134914471 | PLCH2 | Gene | Pathway | associated | |||
| PA33384 | PLCB1 | Gene | Pathway | associated | |||
| PA33385 | PLCB2 | Gene | Pathway | associated | |||
| PA33386 | PLCB3 | Gene | Pathway | associated | |||
| PA33387 | PLCB4 | Gene | Pathway | associated | |||
| PA33388 | PLCD1 | Gene | Pathway | associated | |||
| PA33389 | PLCD3 | Gene | Pathway | associated | |||
| PA33390 | PLCD4 | Gene | Pathway | associated | |||
| PA33391 | PLCE1 | Gene | Pathway | associated | |||
| PA33392 | PLCG1 | Gene | Pathway | associated | 20124951 | ||
| PA33393 | PLCG2 | Gene | Pathway | associated | 20124951 | ||
| PA33394 | PLCL1 | Gene | Pathway | associated | |||
| PA33395 | PLCL2 | Gene | Pathway | associated | |||
| PA34183 | RAF1 | Gene | Pathway | associated | 20124951 | ||
| PA39 | ADRB2 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31875586 | 2020 | PRKCH polymorphism is associated with rheumatoid arthritis in a Chinese population. | 0 |
| 31875586 | 2020 | PRKCH polymorphism is associated with rheumatoid arthritis in a Chinese population. | 0 |
| 29482336 | 2019 | Advanced Oxidation Protein Products Aggravate Tubulointerstitial Fibrosis Through Protein Kinase C-Dependent Mitochondrial Injury in Early Diabetic Nephropathy. | 19 |
| 30562553 | 2019 | Differential effects of protein kinase C-eta on apoptosis versus senescence. | 4 |
| 29482336 | 2019 | Advanced Oxidation Protein Products Aggravate Tubulointerstitial Fibrosis Through Protein Kinase C-Dependent Mitochondrial Injury in Early Diabetic Nephropathy. | 19 |
| 30562553 | 2019 | Differential effects of protein kinase C-eta on apoptosis versus senescence. | 4 |
| 28596089 | 2017 | PRKCH regulates hematopoietic stem cell function and predicts poor prognosis in acute myeloid leukemia. | 7 |
| 28640647 | 2017 | Influence of PRKCH gene polymorphism on antihypertensive response to amlodipine and telmisartan. | 1 |
| 28939105 | 2017 | Protein kinase C-eta regulates Mcl-1 level via ERK1. | 6 |
| 28596089 | 2017 | PRKCH regulates hematopoietic stem cell function and predicts poor prognosis in acute myeloid leukemia. | 7 |
| 28640647 | 2017 | Influence of PRKCH gene polymorphism on antihypertensive response to amlodipine and telmisartan. | 1 |
| 28939105 | 2017 | Protein kinase C-eta regulates Mcl-1 level via ERK1. | 6 |
| 25370935 | 2015 | PRKCH 1425G/A Polymorphism Predicts Recurrence of Ischemic Stroke in a Chinese Population. | 3 |
| 25900926 | 2015 | Protein kinase Cη polymorphism and the susceptibility to ischemic stroke in the Taiwan population. | 2 |
| 26404773 | 2015 | Inhibition of TRPC6 by protein kinase C isoforms in cultured human podocytes. | 5 |
Citation
Dessen P
PRKCH (protein kinase C eta)
Atlas Genet Cytogenet Oncol Haematol. 2004-06-01
Online version: http://atlasgeneticsoncology.org/gene/42912/prkch-(protein-kinase-c-eta)
