FCSK (fucose kinase)

2004-06-01  

Identity

HGNC
FCSK
LOCATION
16q22.1
LOCUSID
197258
ALIAS
1110046B12Rik,CDGF2,FUK
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 197258
MIM: 608675
HGNC: 29500
Ensembl: ENSG00000157353

Variants:

dbSNP: 197258
ClinVar: 197258
TCGA: ENSG00000157353
COSMIC: FCSK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000157353ENST00000288078Q8N0W3
ENSG00000157353ENST00000378912Q8N0W3
ENSG00000157353ENST00000498702J3KTP6
ENSG00000157353ENST00000571514J3KSP6
ENSG00000157353ENST00000572784I3L106
ENSG00000157353ENST00000573352I3L3J1
ENSG00000157353ENST00000574784I3L1X0
ENSG00000157353ENST00000576453I3L171

Pathways

PathwaySourceExternal ID
Fructose and mannose metabolismKEGGko00051
Amino sugar and nucleotide sugar metabolismKEGGko00520
Fructose and mannose metabolismKEGGhsa00051
Amino sugar and nucleotide sugar metabolismKEGGhsa00520
Metabolic pathwaysKEGGhsa01100
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinREACTOMER-HSA-446193
Synthesis of substrates in N-glycan biosythesisREACTOMER-HSA-446219
GDP-fucose biosynthesisREACTOMER-HSA-6787639

References

Pubmed IDYearTitleCitations
387221072024Novel insight into FCSK-congenital disorder of glycosylation through a CRISPR-generated cell model.1
387221072024Novel insight into FCSK-congenital disorder of glycosylation through a CRISPR-generated cell model.1
299248342018The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells.8
299248342018The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells.8

Citation

Dessen P

FCSK (fucose kinase)

Atlas Genet Cytogenet Oncol Haematol. 2004-06-01

Online version: http://atlasgeneticsoncology.org/gene/42914/fcsk-(fucose-kinase)