CEBPD (CCAAT enhancer binding protein delta)

2006-12-01 Affiliation

Identity

HGNC

CEBPD

LOCATION

8q11.21

LOCUSID

1052

ALIAS

C/EBP-delta,CELF,CRP3,NF-IL6-beta

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 1052
MIM: 116898
HGNC: 1835
Ensembl: ENSG00000221869

Variants:

dbSNP: 1052
ClinVar: 1052
TCGA: ENSG00000221869
COSMIC: CEBPD

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000221869	ENST00000408965	P49716

Expression (GTEx)

100

200

300

400

500

600

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Immune System	REACTOME	R-HSA-168256
Cytokine Signaling in Immune system	REACTOME	R-HSA-1280215
Signaling by Interleukins	REACTOME	R-HSA-449147
Developmental Biology	REACTOME	R-HSA-1266738
Transcriptional regulation of white adipocyte differentiation	REACTOME	R-HSA-381340
Interleukin-4 and 13 signaling	REACTOME	R-HSA-6785807

References

Pubmed ID	Year	Title	Citations
17562792	2007	C/EBPdelta regulates cell cycle and self-renewal of human limbal stem cells.	66
12857754	2003	CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation.	52
17234736	2007	The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia.	50
18753137	2008	Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex.	43
19811452	2009	C/EBP transcription factors regulate SREBP1c gene expression during adipogenesis.	40
24155666	2013	The many faces of C/EBPδ and their relevance for inflammation and cancer.	38
11741938	2002	Dynamic regulation of cyclooxygenase-2 promoter activity by isoforms of CCAAT/enhancer-binding proteins.	33
15212823	2004	CCAAT/enhancer binding protein delta (C/EBPdelta) expression and elevation in Alzheimer's disease.	30
15674331	2005	C/EBPdelta expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation.	29
12825852	2003	Expression of the CCAAT/enhancer-binding proteins C/EBPalpha, C/EBPbeta and C/EBPdelta in breast cancer: correlations with clinicopathologic parameters and cell-cycle regulatory proteins.	28

Citation

Dessen P

CEBPD (CCAAT enhancer binding protein delta)

Atlas Genet Cytogenet Oncol Haematol. 2006-12-01

Online version: http://atlasgeneticsoncology.org/gene/42983/cebpd-(ccaat-enhancer-binding-protein-delta)