DCUN1D1 (defective in cullin neddylation 1 domain containing 1)

2006-12-01  

Identity

HGNC
LOCATION
3q26.33
LOCUSID
ALIAS
DCNL1,DCUN1L1,RP42,SCCRO,SCRO,Tes3
FUSION GENES

Other Information

Locus ID:

NCBI: 54165
MIM: 605905
HGNC: 18184
Ensembl: ENSG00000043093

Variants:

dbSNP: 54165
ClinVar: 54165
TCGA: ENSG00000043093
COSMIC: DCUN1D1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000043093ENST00000292782Q96GG9
ENSG00000043093ENST00000460412C9JVE2
ENSG00000043093ENST00000466812C9JRU6
ENSG00000043093ENST00000469954C9JVE2
ENSG00000043093ENST00000487822C9J0B2
ENSG00000043093ENST00000492563F8WC32
ENSG00000043093ENST00000497606C9J8R4
ENSG00000043093ENST00000632685C9JVE2

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375225752023Circ-DTL sponges miR-758-3p to accelerate cervical cancer malignant progression by regulating DCUN1D1 expression.0
375660522023DCUN1D1 Is an Essential Regulator of Prostate Cancer Proliferation and Tumour Growth That Acts through Neddylation of Cullin 1, 3, 4A and 5 and Deregulation of Wnt/Catenin Pathway.1
375225752023Circ-DTL sponges miR-758-3p to accelerate cervical cancer malignant progression by regulating DCUN1D1 expression.0
375660522023DCUN1D1 Is an Essential Regulator of Prostate Cancer Proliferation and Tumour Growth That Acts through Neddylation of Cullin 1, 3, 4A and 5 and Deregulation of Wnt/Catenin Pathway.1
338625572021Evidence for frequent concurrent DCUN1D1, FGFR1, BCL9 gene copy number amplification in squamous cell lung cancer.4
338625572021Evidence for frequent concurrent DCUN1D1, FGFR1, BCL9 gene copy number amplification in squamous cell lung cancer.4
318982372020Targeting DCN1-UBC12 Protein-Protein Interaction for Regulation of Neddylation Pathway.5
318982372020Targeting DCN1-UBC12 Protein-Protein Interaction for Regulation of Neddylation Pathway.5
305282652019DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer.15
305875762019Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.10
305282652019DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer.15
305875762019Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.10
284701462018MicroRNA-520b Functions as a Tumor Suppressor in Colorectal Cancer by Inhibiting Defective in Cullin Neddylation 1 Domain Containing 1 (DCUN1D1).16
291646662018Expression of DCUN1D1 in laryngeal squamous cell carcinoma and its inhibiting effect on TU-177 cells after interfered by RNA.1
284701462018MicroRNA-520b Functions as a Tumor Suppressor in Colorectal Cancer by Inhibiting Defective in Cullin Neddylation 1 Domain Containing 1 (DCUN1D1).16

Citation

Dessen P

DCUN1D1 (defective in cullin neddylation 1 domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-12-01

Online version: http://atlasgeneticsoncology.org/gene/42991/dcun1d1-(defective-in-cullin-neddylation-1-domain-containing-1)