PIM3 (Pim-3 proto-oncogene, serine/threonine kinase)

2005-02-01  

Identity

HGNC
PIM3
LOCATION
22q13.33
LOCUSID
415116
ALIAS
pim-3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 415116
MIM: 610580
HGNC: 19310
Ensembl: ENSG00000198355

Variants:

dbSNP: 415116
ClinVar: 415116
TCGA: ENSG00000198355
COSMIC: PIM3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198355ENST00000360612Q86V86

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
338640242022CRISPR/Cas9-mediated knockout of PIM3 suppresses tumorigenesis and cancer cell stemness in human hepatoblastoma cells.9
338640242022CRISPR/Cas9-mediated knockout of PIM3 suppresses tumorigenesis and cancer cell stemness in human hepatoblastoma cells.9
339284962021Effects of PIM3 in prognosis of colon cancer.5
339284962021Effects of PIM3 in prognosis of colon cancer.5
319944022020Proto-Oncogene Serine/Threonine Kinase PIM3 Promotes Cell Migration via Modulating Rho GTPase Signaling.7
325041812020High Expression of NEK2 and PIM1, but Not PIM3, Is Linked to an Aggressive Phenotype of Bronchopulmonary Neuroendocrine Neoplasms.3
327070332020Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.43
328005542020PIM 3 kinase, a proto-oncogene product, regulates phosphorylation of the measles virus nucleoprotein tail domain at Ser 479 and Ser 510.2
319944022020Proto-Oncogene Serine/Threonine Kinase PIM3 Promotes Cell Migration via Modulating Rho GTPase Signaling.7
325041812020High Expression of NEK2 and PIM1, but Not PIM3, Is Linked to an Aggressive Phenotype of Bronchopulmonary Neuroendocrine Neoplasms.3
327070332020Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.43
328005542020PIM 3 kinase, a proto-oncogene product, regulates phosphorylation of the measles virus nucleoprotein tail domain at Ser 479 and Ser 510.2
310154452019PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation.7
318824282019Effect of Pim-3 Downregulation on Proliferation and Apoptosis in Lung Adenocarcinoma A549 Cells.5
310154452019PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation.7

Citation

Dessen P

PIM3 (Pim-3 proto-oncogene, serine/threonine kinase)

Atlas Genet Cytogenet Oncol Haematol. 2005-02-01

Online version: http://atlasgeneticsoncology.org/gene/43009/pim3-(pim-3-proto-oncogene-serine-threonine-kinase)