Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 201475
MIM: 616448
HGNC: 31332
Ensembl: ENSG00000206418
Variants:
dbSNP: 201475
ClinVar: 201475
TCGA: ENSG00000206418
COSMIC: RAB12
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000206418 | ENST00000329286 | Q6IQ22 |
| ENSG00000206418 | ENST00000649141 | A0A3B3ITT1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38920696 | 2024 | Reduced Retinal Pigment Epithelial Autophagy Due to Loss of Rab12 Prenylation in a Human iPSC-RPE Model of Choroideremia. | 0 |
| 38920696 | 2024 | Reduced Retinal Pigment Epithelial Autophagy Due to Loss of Rab12 Prenylation in a Human iPSC-RPE Model of Choroideremia. | 0 |
| 36739948 | 2023 | The clathrin adaptor complex-1 and Rab12 regulate post-golgi trafficking of WT epidermal growth factor receptor (EGFR). | 2 |
| 37207563 | 2023 | LRRK2-mediated phosphorylation and thermal stability of Rab12 are regulated by bound nucleotides. | 1 |
| 37874617 | 2023 | Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes. | 4 |
| 36739948 | 2023 | The clathrin adaptor complex-1 and Rab12 regulate post-golgi trafficking of WT epidermal growth factor receptor (EGFR). | 2 |
| 37207563 | 2023 | LRRK2-mediated phosphorylation and thermal stability of Rab12 are regulated by bound nucleotides. | 1 |
| 37874617 | 2023 | Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes. | 4 |
| 29352104 | 2018 | A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy. | 9 |
| 29352104 | 2018 | A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy. | 9 |
| 28249939 | 2017 | Regulation of DENND3, the exchange factor for the small GTPase Rab12 through an intramolecular interaction. | 7 |
| 28249939 | 2017 | Regulation of DENND3, the exchange factor for the small GTPase Rab12 through an intramolecular interaction. | 7 |
| 25925668 | 2015 | Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy. | 37 |
| 25925668 | 2015 | Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy. | 37 |
| 24703428 | 2014 | Rab12 localizes to Shiga toxin-induced plasma membrane invaginations and controls toxin transport. | 9 |
Citation
Dessen P
RAB12 (RAB12, member RAS oncogene family)
Atlas Genet Cytogenet Oncol Haematol. 2005-11-01
Online version: http://atlasgeneticsoncology.org/gene/43038/rab12-(rab12-member-ras-oncogene-family)
