Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
ICBP90,Np95,RNF106,TDRD22,hNP95,hUHRF1,huNp95
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29128
MIM: 607990
HGNC: 12556
Ensembl: ENSG00000276043
Variants:
dbSNP: 29128
ClinVar: 29128
TCGA: ENSG00000276043
COSMIC: UHRF1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Epigenetic regulation of gene expression | REACTOME | R-HSA-212165 |
| DNA methylation | REACTOME | R-HSA-5334118 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38055118 | 2024 | Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy. | 0 |
| 38411080 | 2024 | CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. | 0 |
| 38580649 | 2024 | Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells. | 0 |
| 38643728 | 2024 | UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis. | 0 |
| 38657333 | 2024 | UHRF1 inhibition mitigates vascular endothelial cell injury and ameliorates atherosclerosis in mice via regulating the SMAD7/YAP1 axis. | 0 |
| 38683130 | 2024 | YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis. | 0 |
| 38789534 | 2024 | The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling. | 0 |
| 38898124 | 2024 | Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3. | 0 |
| 38055118 | 2024 | Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy. | 0 |
| 38411080 | 2024 | CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. | 0 |
| 38580649 | 2024 | Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells. | 0 |
| 38643728 | 2024 | UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis. | 0 |
| 38657333 | 2024 | UHRF1 inhibition mitigates vascular endothelial cell injury and ameliorates atherosclerosis in mice via regulating the SMAD7/YAP1 axis. | 0 |
| 38683130 | 2024 | YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis. | 0 |
| 38789534 | 2024 | The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling. | 0 |
Citation
Dessen P
UHRF1 (ubiquitin like with PHD and ring finger domains 1)
Atlas Genet Cytogenet Oncol Haematol. 2005-11-01
Online version: http://atlasgeneticsoncology.org/gene/43071/uhrf1-(ubiquitin-like-with-phd-and-ring-finger-domains-1)
