Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51231
HGNC: 18996
Ensembl: ENSG00000105053
Variants:
dbSNP: 51231
ClinVar: 51231
TCGA: ENSG00000105053
COSMIC: VRK3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33067254 | 2020 | RNF144a induces ERK-dependent cell death under oxidative stress via downregulation of vaccinia-related kinase 3. | 3 |
| 33067254 | 2020 | RNF144a induces ERK-dependent cell death under oxidative stress via downregulation of vaccinia-related kinase 3. | 3 |
| 31324890 | 2019 | A kinome-wide shRNA screen uncovers vaccinia-related kinase 3 (VRK3) as an essential gene for diffuse intrinsic pontine glioma survival. | 10 |
| 31324890 | 2019 | A kinome-wide shRNA screen uncovers vaccinia-related kinase 3 (VRK3) as an essential gene for diffuse intrinsic pontine glioma survival. | 10 |
| 28412365 | 2017 | Vaccinia-related kinase 3 (VRK3) sets the circadian period and amplitude by affecting the subcellular localization of clock proteins in mammalian cells. | 1 |
| 28927264 | 2017 | Comparative Interactomes of VRK1 and VRK3 with Their Distinct Roles in the Cell Cycle of Liver Cancer. | 7 |
| 28412365 | 2017 | Vaccinia-related kinase 3 (VRK3) sets the circadian period and amplitude by affecting the subcellular localization of clock proteins in mammalian cells. | 1 |
| 28927264 | 2017 | Comparative Interactomes of VRK1 and VRK3 with Their Distinct Roles in the Cell Cycle of Liver Cancer. | 7 |
| 27346674 | 2016 | Stress-induced nuclear translocation of CDK5 suppresses neuronal death by downregulating ERK activation via VRK3 phosphorylation. | 8 |
| 27941812 | 2016 | VRK3-mediated nuclear localization of HSP70 prevents glutamate excitotoxicity-induced apoptosis and Aβ accumulation via enhancement of ERK phosphatase VHR activity. | 8 |
| 27346674 | 2016 | Stress-induced nuclear translocation of CDK5 suppresses neuronal death by downregulating ERK activation via VRK3 phosphorylation. | 8 |
| 27941812 | 2016 | VRK3-mediated nuclear localization of HSP70 prevents glutamate excitotoxicity-induced apoptosis and Aβ accumulation via enhancement of ERK phosphatase VHR activity. | 8 |
| 25899223 | 2015 | Presumed pseudokinase VRK3 functions as a BAF kinase. | 17 |
| 25899223 | 2015 | Presumed pseudokinase VRK3 functions as a BAF kinase. | 17 |
| 23082977 | 2013 | Role of bivalent cations in structural stabilities of new drug targets--vaccinia-related kinases (VRK) from molecular dynamics simulations. | 1 |
Citation
Dessen P
VRK3 (VRK serine/threonine kinase 3)
Atlas Genet Cytogenet Oncol Haematol. 2005-11-01
Online version: http://atlasgeneticsoncology.org/gene/43075/vrk3-(vrk-serine-threonine-kinase-3)
