ZFPM2 (zinc finger protein, FOG family member 2)

2004-05-01  

Identity

HGNC
ZFPM2
LOCATION
8q23.1
LOCUSID
23414
ALIAS
DIH3,FOG2,SRXY9,ZC2HC11B,ZNF89B,hFOG-2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23414
MIM: 603693
HGNC: 16700
Ensembl: ENSG00000169946

Variants:

dbSNP: 23414
ClinVar: 23414
TCGA: ENSG00000169946
COSMIC: ZFPM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169946ENST00000407775Q8WW38
ENSG00000169946ENST00000517361E7ET52
ENSG00000169946ENST00000520027E5RJX0
ENSG00000169946ENST00000520492E7ET52

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381891502024A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.0
381891502024A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.0
333405462021Long noncoding RNA CCDC26 as a modulator of transcriptional switching between fetal and embryonic globins.2
333405462021Long noncoding RNA CCDC26 as a modulator of transcriptional switching between fetal and embryonic globins.2
319199932020LncRNA ZFPM2-AS1 promotes lung adenocarcinoma progression by interacting with UPF1 to destabilize ZFPM2.32
319620122020Analysis of variants in GATA4 and FOG2/ZFPM2 demonstrates benign contribution to 46,XY disorders of sex development.11
326333642020EphA3 promotes the proliferation of NPC cells through negatively regulating the ability of FOG2.1
319199932020LncRNA ZFPM2-AS1 promotes lung adenocarcinoma progression by interacting with UPF1 to destabilize ZFPM2.32
319620122020Analysis of variants in GATA4 and FOG2/ZFPM2 demonstrates benign contribution to 46,XY disorders of sex development.11
326333642020EphA3 promotes the proliferation of NPC cells through negatively regulating the ability of FOG2.1
290189782018Identification of ZFPM2 mutations in sporadic conotruncal heart defect patients.4
299721252018[Association of single nucleotide polymorphisms of transcription factors with congenital heart diseases in the Chinese population: a Meta analysis].1
290189782018Identification of ZFPM2 mutations in sporadic conotruncal heart defect patients.4
299721252018[Association of single nucleotide polymorphisms of transcription factors with congenital heart diseases in the Chinese population: a Meta analysis].1
283731602017Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor.53

Citation

Dessen P

ZFPM2 (zinc finger protein, FOG family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2004-05-01

Online version: http://atlasgeneticsoncology.org/gene/431/zfpm2-(zinc-finger-protein-fog-family-member-2)