Identity
HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
AATYK,AATYK1,LMR1,LMTK1,PPP1R77,p35BP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9625
MIM: 605276
HGNC: 21
Ensembl: ENSG00000181409
Variants:
dbSNP: 9625
ClinVar: 9625
TCGA: ENSG00000181409
COSMIC: AATK
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34523681 | 2022 | Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1. | 4 |
| 35902728 | 2022 | Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner. | 4 |
| 34523681 | 2022 | Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1. | 4 |
| 35902728 | 2022 | Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner. | 4 |
| 27485693 | 2016 | Downregulation of AATK mediates microRNA-558-induced resistance of A549 cells to radiotherapy. | 5 |
| 27485693 | 2016 | Downregulation of AATK mediates microRNA-558-induced resistance of A549 cells to radiotherapy. | 5 |
| 17651901 | 2007 | Structural and functional analysis of the apoptosis-associated tyrosine kinase (AATYK) family. | 25 |
| 17651901 | 2007 | Structural and functional analysis of the apoptosis-associated tyrosine kinase (AATYK) family. | 25 |
| 14521924 | 2003 | Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein. | 10 |
| 14521924 | 2003 | Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein. | 10 |
Citation
Dessen P
AATK (apoptosis associated tyrosine kinase)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43100/aatk-(apoptosis-associated-tyrosine-kinase)
