CDK15 (cyclin dependent kinase 15)

2006-10-01  

Identity

HGNC
CDK15
LOCATION
2q33.1
LOCUSID
65061
ALIAS
ALS2CR7,PFTAIRE2,PFTK2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 65061
MIM: 616147
HGNC: 14434
Ensembl: ENSG00000138395

Variants:

dbSNP: 65061
ClinVar: 65061
TCGA: ENSG00000138395
COSMIC: CDK15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138395ENST00000260967Q96Q40
ENSG00000138395ENST00000410091Q96Q40
ENSG00000138395ENST00000434439Q96Q40
ENSG00000138395ENST00000450471Q96Q40
ENSG00000138395ENST00000451080F8WDP7
ENSG00000138395ENST00000652192Q96Q40

Expression (GTEx)

0
1
2
3
4
5
6
7
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
342621442022CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway.19
342621442022CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway.19
341622682021Cyclin-dependent kinase 15 upregulation is correlated with poor prognosis for patients with breast cancer.0
341622682021Cyclin-dependent kinase 15 upregulation is correlated with poor prognosis for patients with breast cancer.0
248662472014ALS2CR7 (CDK15) attenuates TRAIL induced apoptosis by inducing phosphorylation of survivin Thr34.24
248662472014ALS2CR7 (CDK15) attenuates TRAIL induced apoptosis by inducing phosphorylation of survivin Thr34.24

Citation

Dessen P

CDK15 (cyclin dependent kinase 15)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43117/css/lib/img/welcome