ARHGAP10 (Rho GTPase activating protein 10)

2006-10-01  

Identity

HGNC
LOCATION
4q31.23
LOCUSID
ALIAS
GRAF2,PS-GAP,PSGAP
FUSION GENES

Other Information

Locus ID:

NCBI: 79658
MIM: 609746
HGNC: 26099
Ensembl: ENSG00000071205

Variants:

dbSNP: 79658
ClinVar: 79658
TCGA: ENSG00000071205
COSMIC: ARHGAP10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000071205ENST00000336498A1A4S6
ENSG00000071205ENST00000336498A0A2X0SFB3
ENSG00000071205ENST00000507661H0Y8W5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Bacterial invasion of epithelial cellsKEGGko05100
Bacterial invasion of epithelial cellsKEGGhsa05100
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840
Programmed Cell DeathREACTOMER-HSA-5357801
ApoptosisREACTOMER-HSA-109581
Regulation of ApoptosisREACTOMER-HSA-169911
Regulation of PAK-2p34 activity by PS-GAP/RHG10REACTOMER-HSA-211728

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
201583042010A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.52
203322632010A genome-wide association study of prognosis in breast cancer.43
270108582016ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells.20
154718512004Identification and characterization of PS-GAP as a novel regulator of caspase-activated PAK-2.9
199110112010Mutation of ARHGAP9 in patients with coronary spastic angina.5
314457072019CXCL12 promotes human ovarian cancer cell invasion through suppressing ARHGAP10 expression.0

Citation

Dessen P

ARHGAP10 (Rho GTPase activating protein 10)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43130/arhgap10-(rho-gtpase-activating-protein-10)