Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 94134
MIM: 610577
HGNC: 16348
Ensembl: ENSG00000165322
Variants:
dbSNP: 94134
ClinVar: 94134
TCGA: ENSG00000165322
COSMIC: ARHGAP12
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447197 | Attention Deficit Disorder with Hyperactivity | Disease | ClinicalAnnotation | associated | PD | 29382897 | |
| PA450464 | methylphenidate | Chemical | ClinicalAnnotation | associated | PD | 29382897 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 18984674 | 2009 | KIF5B gene sequence variation and response of cardiac stroke volume to regular exercise. | 11 |
| 18984674 | 2009 | KIF5B gene sequence variation and response of cardiac stroke volume to regular exercise. | 11 |
| 18504429 | 2008 | Met-driven invasive growth involves transcriptional regulation of Arhgap12. | 18 |
| 18504429 | 2008 | Met-driven invasive growth involves transcriptional regulation of Arhgap12. | 18 |
| 18504429 | 2008 | Met-driven invasive growth involves transcriptional regulation of Arhgap12. | 18 |
| 18504429 | 2008 | Met-driven invasive growth involves transcriptional regulation of Arhgap12. | 18 |
| 16385451 | 2006 | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. | 83 |
| 16385451 | 2006 | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. | 83 |
| 11854031 | 2002 | Cloning and characterization of ARHGAP12, a novel human rhoGAP gene. | 5 |
| 11854031 | 2002 | Cloning and characterization of ARHGAP12, a novel human rhoGAP gene. | 5 |
Citation
Dessen P
ARHGAP12 (Rho GTPase activating protein 12)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43132/arhgap12-(rho-gtpase-activating-protein-12)
