ARHGAP22 (Rho GTPase activating protein 22)

2006-10-01  

Identity

HGNC
LOCATION
10q11.22
LOCUSID
ALIAS
RhoGAP2,RhoGap22
FUSION GENES

Other Information

Locus ID:

NCBI: 58504
MIM: 610585
HGNC: 30320
Ensembl: ENSG00000128805

Variants:

dbSNP: 58504
ClinVar: 58504
TCGA: ENSG00000128805
COSMIC: ARHGAP22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128805ENST00000249601Q7Z5H3
ENSG00000128805ENST00000374170A6NJ38
ENSG00000128805ENST00000374172A6NHM7
ENSG00000128805ENST00000417247Q7Z5H3
ENSG00000128805ENST00000417912Q7Z5H3
ENSG00000128805ENST00000417912A0A2X0SFC0
ENSG00000128805ENST00000435790Q7Z5H3
ENSG00000128805ENST00000460425D6RBJ8
ENSG00000128805ENST00000477708D6R9V6

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
213104922011Genome-wide association study of diabetic retinopathy in a Taiwanese population.47
219264142011The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2.41
219696042011Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin.5
229525832012The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 has 1:2 stoichiometry and a single peptide binding mode.3
285445092017Association of ARHGAP22 gene polymorphisms with the risk of type 2 diabetic retinopathy.0
319767612020Associations of rs2300782 CAMK4, rs2292239 ERBB3 and rs10491034 ARHGAP22 with Diabetic Retinopathy Among Chinese Hui Population.0

Citation

Dessen P

ARHGAP22 (Rho GTPase activating protein 22)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43138/arhgap22-(rho-gtpase-activating-protein-22)